Cell‐by‐cell quantification of the androgen receptor in benign and malignant prostate leads to a better understanding of changes linked to cancer initiation and progression

Cell‐by‐cell quantification of the androgen receptor in benign and malignant prostate leads to a better understanding of changes linked to cancer initiation and progression

Abstract The androgen receptor (AR) plays a crucial role in the development and homeostasis of the prostate and is a key therapeutic target in prostate cancer (PCa). The gold standard therapy for advanced PCa is androgen deprivation therapy (ADT), which targets androgen production and AR signaling....

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Bibliographic Details
Main Authors: Seta Derderian, Tarik Benidir, Eleonora Scarlata, Turki Altaylouni, Lucie Hamel, Fatima Zahra Zouanat, Fadi Brimo, Armen Aprikian, Simone Chevalier
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:The Journal of Pathology: Clinical Research
Subjects:
prostate cancer
castration resistant prostate cancer
metastasis
androgen deprivation therapy
androgen receptor
AR
Online Access:https://doi.org/10.1002/cjp2.319

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