Metformin inhibits the apoptosis of intervertebral disc tissue cells in rabbit model with lumbar intervertebral disc degeneration

Metformin inhibits the apoptosis of intervertebral disc tissue cells in rabbit model with lumbar intervertebral disc degeneration

Objective To investigate the impacts of metformin on autophagy and inflammation of intervertebral disc tissue in rabbits, so as to preliminarily explore the molecular mechanism of its anti-intervertebral disc degeneration. Methods The rabbits were diveded into: sham operation group, model group, met...

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Bibliographic Details
Main Author:	DONG Junli, CAI Shaokang, YAN Lei, CAI Yi
Format:	Article
Language:	zho
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2023-01-01
Series:	Jichu yixue yu linchuang
Subjects:	metformin\|lumbar intervertebral disc degeneration\|intervertebral disc tissue\|autophagy\|apoptosis
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-1-116.pdf

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