Chiral phosphoric acid-catalyzed transfer hydrogenation of 3,3-difluoro-3H-indoles

Chiral phosphoric acid-catalyzed transfer hydrogenation of 3,3-difluoro-3H-indoles

A convenient and efficient method for the synthesis of optically active difluoro-substituted indoline derivatives starting from the corresponding 3H-indoles by chiral phosphoric acid-catalyzed transfer hydrogenation was developed. Using Hantzsch ester as the hydrogen source under mild reaction condi...

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Bibliographic Details
Main Authors:	Yumei Wang, Guangzhu Wang, Yanping Zhu, Kaiwu Dong
Format:	Article
Language:	English
Published:	Beilstein-Institut 2024-02-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	asymmetric organocatalysis chiral brønsted acid 3,3-difluoroindoline hantzsch ester transfer hydrogenation
Online Access:	https://doi.org/10.3762/bjoc.20.20

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