Current Status of Raf Kinase Inhibitor Protein (RKIP) in Lung Cancer: Behind RTK Signaling

Current Status of Raf Kinase Inhibitor Protein (RKIP) in Lung Cancer: Behind RTK Signaling

Lung cancer is the most deadly neoplasm with the highest incidence in both genders, with non-small cell lung cancer (NSCLC) being the most frequent subtype. Somatic mutations within the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene are key drivers of NSCLC progression, w...

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Bibliographic Details
Main Authors: Ana Raquel-Cunha, Diana Cardoso-Carneiro, Rui M. Reis, Olga Martinho
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
lung cancer
EGFR
RKIP signaling
prognosis
cancer therapy
Online Access:https://www.mdpi.com/2073-4409/8/5/442

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