A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program

<p>Abstract</p> <p>Background</p> <p>We investigated whether macronutrient composition of energy-restricted diets influences the efficacy of a telemedically guided weight loss program.</p> <p>Methods</p> <p>Two hundred overweight subjects were ra...

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Main Authors: Stehle Peter, Kleesiek Knut, Kuhn Joachim, Götting Christian, Berthold Heiner K, Zittermann Armin, Frisch Sabine, Körtke Heinrich
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Cardiovascular Diabetology
Online Access:http://www.cardiab.com/content/8/1/36
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author Stehle Peter
Kleesiek Knut
Kuhn Joachim
Götting Christian
Berthold Heiner K
Zittermann Armin
Frisch Sabine
Körtke Heinrich
author_facet Stehle Peter
Kleesiek Knut
Kuhn Joachim
Götting Christian
Berthold Heiner K
Zittermann Armin
Frisch Sabine
Körtke Heinrich
author_sort Stehle Peter
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>We investigated whether macronutrient composition of energy-restricted diets influences the efficacy of a telemedically guided weight loss program.</p> <p>Methods</p> <p>Two hundred overweight subjects were randomly assigned to a conventional low-fat diet and a low-carbohydrate diet group (target carbohydrate content: >55% energy and <40% energy, respectively). Both groups attended a weekly nutrition education program and dietary counselling by telephone, and had to transfer actual body weight data to our clinic weekly with added Bluetooth<sup>® </sup>technology by mobile phone. Various fatness and fat distribution parameters, energy and macronutrient intake, and various biochemical risk markers were measured at baseline and after 6, and 12 months.</p> <p>Results</p> <p>In both groups, energy intake decreased by 400 kcal/d compared to baseline values within the first 6 months and slightly increased again within the second 6 months. Macronutrient composition differed significantly between the groups from the beginning to month 12. At study termination, weight loss was 5.8 kg (SD: 6.1 kg) in the low-carbohydrate group and 4.3 kg (SD: 5.1 kg) in the low-fat group (p = 0.065). In the low-carbohydrate group, triglyceride and HDL-cholesterol levels were lower at month 6 and waist circumference and systolic blood pressure were lower at month 12 compared with the low-fat group (P = 0.005–0.037). Other risk markers improved to a similar extent in both groups.</p> <p>Conclusion</p> <p>Despite favourable effects of both diets on weight loss, the carbohydrate-reduced diet was more beneficial with respect to cardiovascular risk factors compared to the fat-reduced diet. Nevertheless, compliance with a weight loss program appears to be even a more important factor for success in prevention and treatment of obesity than the composition of the diet.</p> <p>Trial registration</p> <p>Clinicaltrials.gov as NCT00868387</p>
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spelling doaj.art-3b0c3cd7656c4663977c3b195c00c9b42022-12-22T03:00:34ZengBMCCardiovascular Diabetology1475-28402009-07-01813610.1186/1475-2840-8-36A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss programStehle PeterKleesiek KnutKuhn JoachimGötting ChristianBerthold Heiner KZittermann ArminFrisch SabineKörtke Heinrich<p>Abstract</p> <p>Background</p> <p>We investigated whether macronutrient composition of energy-restricted diets influences the efficacy of a telemedically guided weight loss program.</p> <p>Methods</p> <p>Two hundred overweight subjects were randomly assigned to a conventional low-fat diet and a low-carbohydrate diet group (target carbohydrate content: >55% energy and <40% energy, respectively). Both groups attended a weekly nutrition education program and dietary counselling by telephone, and had to transfer actual body weight data to our clinic weekly with added Bluetooth<sup>® </sup>technology by mobile phone. Various fatness and fat distribution parameters, energy and macronutrient intake, and various biochemical risk markers were measured at baseline and after 6, and 12 months.</p> <p>Results</p> <p>In both groups, energy intake decreased by 400 kcal/d compared to baseline values within the first 6 months and slightly increased again within the second 6 months. Macronutrient composition differed significantly between the groups from the beginning to month 12. At study termination, weight loss was 5.8 kg (SD: 6.1 kg) in the low-carbohydrate group and 4.3 kg (SD: 5.1 kg) in the low-fat group (p = 0.065). In the low-carbohydrate group, triglyceride and HDL-cholesterol levels were lower at month 6 and waist circumference and systolic blood pressure were lower at month 12 compared with the low-fat group (P = 0.005–0.037). Other risk markers improved to a similar extent in both groups.</p> <p>Conclusion</p> <p>Despite favourable effects of both diets on weight loss, the carbohydrate-reduced diet was more beneficial with respect to cardiovascular risk factors compared to the fat-reduced diet. Nevertheless, compliance with a weight loss program appears to be even a more important factor for success in prevention and treatment of obesity than the composition of the diet.</p> <p>Trial registration</p> <p>Clinicaltrials.gov as NCT00868387</p>http://www.cardiab.com/content/8/1/36
spellingShingle Stehle Peter
Kleesiek Knut
Kuhn Joachim
Götting Christian
Berthold Heiner K
Zittermann Armin
Frisch Sabine
Körtke Heinrich
A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
Cardiovascular Diabetology
title A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
title_full A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
title_fullStr A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
title_full_unstemmed A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
title_short A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program
title_sort randomized controlled trial on the efficacy of carbohydrate reduced or fat reduced diets in patients attending a telemedically guided weight loss program
url http://www.cardiab.com/content/8/1/36
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