Evaluation of sciatic nerve damage following intraneural injection of bupivacaine, levobupivacaine and lidocaine in rats

Objective: The local anesthetics may cause neurotoxicity. We aimed to compare the neurotoxic potential of different local anesthetics, local anesthetic induced nerve damage and pathological changes of a peripheral nerve. Methods: Sixty Wistar rats weighing 200–350 g were studied. Rats were assigned...

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Bibliographic Details
Main Authors: Oznur Sen, Nevzat Cem Sayilgan, Ayse Cigdem Tutuncu, Mefkur Bakan, Guniz Meyanci Koksal, Huseyin Oz
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Brazilian Journal of Anesthesiology
Online Access:http://www.sciencedirect.com/science/article/pii/S0104001415000172