Effects of Phosphorylation on the Activity, Inhibition and Stability of Carbonic Anhydrases

Effects of Phosphorylation on the Activity, Inhibition and Stability of Carbonic Anhydrases

Carbonic anhydrases (CAs) are a metalloenzyme family that have important roles in cellular processes including pH homeostasis and have been implicated in multiple pathological conditions. Small molecule inhibitors have been developed to target carbonic anhydrases, but the effects of post-translation...

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Bibliographic Details
Main Authors:	Xiaojing Huang, Daniel Winter, Dominic J. Glover, Claudiu T. Supuran, William A. Donald
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	International Journal of Molecular Sciences
Subjects:	human carbonic anhydrase I human carbonic anhydrase II post-translational modifications phosphorylation sulphonamides esterase activity
Online Access:	https://www.mdpi.com/1422-0067/24/11/9275

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