Maternal effect genes: Update and review of evidence for a link with birth defects
Summary: Maternal effect genes (MEGs) encode factors (e.g., RNA) that are present in the oocyte and required for early embryonic development. Hence, while these genes and gene products are of maternal origin, their phenotypic consequences result from effects on the embryo. The first mammalian MEGs w...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | HGG Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666247721000488 |