Maternal effect genes: Update and review of evidence for a link with birth defects

Maternal effect genes: Update and review of evidence for a link with birth defects

Summary: Maternal effect genes (MEGs) encode factors (e.g., RNA) that are present in the oocyte and required for early embryonic development. Hence, while these genes and gene products are of maternal origin, their phenotypic consequences result from effects on the embryo. The first mammalian MEGs w...

Full description

Bibliographic Details
Main Author: Laura E. Mitchell
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:HGG Advances
Subjects:
development
embryo
gene
human
malformation
maternal
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247721000488

Similar Items

Similar Items