HiC-GNN: A generalizable model for 3D chromosome reconstruction using graph convolutional neural networks

Chromosome conformation capture (3 C) is a method of measuring chromosome topology in terms of loci interaction. The Hi-C method is a derivative of 3 C that allows for genome-wide quantification of chromosome interaction. From such interaction data, it is possible to infer the three-dimensional (3D)...

Full description

Bibliographic Details
Main Authors: Van Hovenga, Jugal Kalita, Oluwatosin Oluwadare
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022006122