Virtual screening and molecular dynamic simulations of the antimalarial derivatives of 2-anilino 4-amino substituted quinazolines docked against a Pf-DHODH protein target

Virtual screening and molecular dynamic simulations of the antimalarial derivatives of 2-anilino 4-amino substituted quinazolines docked against a Pf-DHODH protein target

Research highlights The research aimed at screening of the antimalarial derivatives of 2-anilino 4-amino substituted quinazolines docked against a Pf-DHODH protein target. Hence, some of the highlights are listed below: 1. The developed derivatives were discovered to follow Lipinski's rule of f...

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Bibliographic Details
Main Authors: Zakari Ya’u Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Stephen Eyije Abechi, Sulaiman Isyaku
Format: Article
Language:English
Published: SpringerOpen 2022-08-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Virtual screening
Antimalarial
Docking
Dynamic simulation
2-Anilino 4-amino substituted quinazolines
And Pf-DHODH
Online Access:https://doi.org/10.1186/s43042-022-00329-2

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