Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens
<p>Summary</p> <p>We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies...
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| Format: | Article |
| Language: | English |
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BMC
2006-09-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/3/1/71 |
| _version_ | 1819202697447866368 |
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| author | Dawson Alistair Buckley Alan Gould Ernest A |
| author_facet | Dawson Alistair Buckley Alan Gould Ernest A |
| author_sort | Dawson Alistair |
| collection | DOAJ |
| description | <p>Summary</p> <p>We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies to WNV in hatchlings declined within three weeks. During the following months, healthy chickens developed WNV neutralizing antibodies that were confirmed by immunoblotting and indirect immunofluorescence tests using WNV antigens. The proportion of seropositive chickens was higher for WNV than for Usutu virus or Sindbis virus. Attempts to isolate infectious virus or to detect viral RNA in the sera, failed.</p> |
| first_indexed | 2024-12-23T04:08:08Z |
| format | Article |
| id | doaj.art-3b17a1fee4304380a89736c8e68efb93 |
| institution | Directory Open Access Journal |
| issn | 1743-422X |
| language | English |
| last_indexed | 2024-12-23T04:08:08Z |
| publishDate | 2006-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Virology Journal |
| spelling | doaj.art-3b17a1fee4304380a89736c8e68efb932022-12-21T18:00:34ZengBMCVirology Journal1743-422X2006-09-01317110.1186/1743-422X-3-71Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickensDawson AlistairBuckley AlanGould Ernest A<p>Summary</p> <p>We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies to WNV in hatchlings declined within three weeks. During the following months, healthy chickens developed WNV neutralizing antibodies that were confirmed by immunoblotting and indirect immunofluorescence tests using WNV antigens. The proportion of seropositive chickens was higher for WNV than for Usutu virus or Sindbis virus. Attempts to isolate infectious virus or to detect viral RNA in the sera, failed.</p>http://www.virologyj.com/content/3/1/71 |
| spellingShingle | Dawson Alistair Buckley Alan Gould Ernest A Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens Virology Journal |
| title | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
| title_full | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
| title_fullStr | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
| title_full_unstemmed | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
| title_short | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
| title_sort | detection of seroconversion to west nile virus usutu virus and sindbis virus in uk sentinel chickens |
| url | http://www.virologyj.com/content/3/1/71 |
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