Identification of HDV-like theta ribozymes involved in tRNA-based recoding of gut bacteriophages

Abstract Trillions of microorganisms, collectively known as the microbiome, inhabit our bodies with the gut microbiome being of particular interest in biomedical research. Bacteriophages, the dominant virome constituents, can utilize suppressor tRNAs to switch to alternative genetic codes (e.g., the...

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Bibliographic Details
Main Authors: Kasimir Kienbeck, Lukas Malfertheiner, Susann Zelger-Paulus, Silke Johannsen, Christian von Mering, Roland K. O. Sigel
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45653-w

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