Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination.

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination.

The genes encoding members of the wingless-related MMTV integration site (WNT) and fibroblast growth factor (FGF) families coordinate growth, morphogenesis, and differentiation in many fields of cells during development. In the mouse, Fgf9 and Wnt4 are expressed in gonads of both sexes prior to sex...

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Bibliographic Details
Main Authors:	Yuna Kim, Akio Kobayashi, Ryohei Sekido, Leo DiNapoli, Jennifer Brennan, Marie-Christine Chaboissier, Francis Poulat, Richard R Behringer, Robin Lovell-Badge, Blanche Capel
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2006-06-01
Series:	PLoS Biology
Online Access:	https://doi.org/10.1371/journal.pbio.0040187

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