Novel Allele Detection Tool Benchmark and Application With Antibody Repertoire Sequencing Dataset

Novel Allele Detection Tool Benchmark and Application With Antibody Repertoire Sequencing Dataset

Detailed knowledge of the diverse immunoglobulin germline genes is critical for the study of humoral immunity. Hundreds of alleles have been discovered by analyzing antibody repertoire sequencing (Rep-seq or Ig-seq) data via multiple novel allele detection tools (NADTs). However, the performance of...

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Bibliografiska uppgifter
Huvudupphovsmän: Xiujia Yang, Yan Zhu, Sen Chen, Huikun Zeng, Junjie Guan, Qilong Wang, Chunhong Lan, Deqiang Sun, Xueqing Yu, Zhenhai Zhang
Materialtyp: Artikel
Språk:English
Publicerad: Frontiers Media S.A. 2021-10-01
Serie:Frontiers in Immunology
Ämnen:
tools benchmarking
novel allele
antibody repertoire
high-throughput sequencing
Ig-seq
Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2021.739179/full

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