A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices

Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressiv...

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Bibliographic Details
Main Authors: Deirdre Kelly, MBBCh, Sarah Mc Erlean, MBBCh, Danielle Byrne, MBBCh, Peter Mac Mahon, MBBCh, John Mc Caffrey, MBBCh
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Radiology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043316300528
Description
Summary:Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting.
ISSN:1930-0433