A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices
Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressiv...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-09-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043316300528 |
| _version_ | 1819156725845983232 |
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| author | Deirdre Kelly, MBBCh Sarah Mc Erlean, MBBCh Danielle Byrne, MBBCh Peter Mac Mahon, MBBCh John Mc Caffrey, MBBCh |
| author_facet | Deirdre Kelly, MBBCh Sarah Mc Erlean, MBBCh Danielle Byrne, MBBCh Peter Mac Mahon, MBBCh John Mc Caffrey, MBBCh |
| author_sort | Deirdre Kelly, MBBCh |
| collection | DOAJ |
| description | Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting. |
| first_indexed | 2024-12-22T15:57:26Z |
| format | Article |
| id | doaj.art-3b1b85f616ad48faa9b983aec1519563 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-22T15:57:26Z |
| publishDate | 2016-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-3b1b85f616ad48faa9b983aec15195632022-12-21T18:20:44ZengElsevierRadiology Case Reports1930-04332016-09-0111322222610.1016/j.radcr.2016.04.009A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practicesDeirdre Kelly, MBBCh0Sarah Mc Erlean, MBBCh1Danielle Byrne, MBBCh2Peter Mac Mahon, MBBCh3John Mc Caffrey, MBBCh4Department of Oncology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, IrelandDepartment of Oncology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, IrelandDepartment of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, IrelandDepartment of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, IrelandDepartment of Oncology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, IrelandGiant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting.http://www.sciencedirect.com/science/article/pii/S1930043316300528Giant Cell TumorRadiological FeaturesDenosumab |
| spellingShingle | Deirdre Kelly, MBBCh Sarah Mc Erlean, MBBCh Danielle Byrne, MBBCh Peter Mac Mahon, MBBCh John Mc Caffrey, MBBCh A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices Radiology Case Reports Giant Cell Tumor Radiological Features Denosumab |
| title | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
| title_full | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
| title_fullStr | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
| title_full_unstemmed | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
| title_short | A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
| title_sort | case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices |
| topic | Giant Cell Tumor Radiological Features Denosumab |
| url | http://www.sciencedirect.com/science/article/pii/S1930043316300528 |
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