Twin arginine translocation, ammonia incorporation, and polyamine biosynthesis are crucial for Proteus mirabilis fitness during bloodstream infection.
The Gram-negative bacterium Proteus mirabilis is a common cause of catheter-associated urinary tract infections (CAUTI), which can progress to secondary bacteremia. While numerous studies have investigated experimental infection with P. mirabilis in the urinary tract, little is known about pathogene...
Main Authors: | Chelsie E Armbruster, Valerie S Forsyth, Alexandra O Johnson, Sara N Smith, Ashley N White, Aimee L Brauer, Brian S Learman, Lili Zhao, Weisheng Wu, Mark T Anderson, Michael A Bachman, Harry L T Mobley |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-04-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1007653 |
Similar Items
-
Differential Contribution of Hydrogen Metabolism to <i>Proteus mirabilis</i> Fitness during Single-Species and Polymicrobial Catheterized Urinary Tract Infection
by: Aimee L. Brauer, et al.
Published: (2023-11-01) -
Metabolic interplay between Proteus mirabilis and Enterococcus faecalis facilitates polymicrobial biofilm formation and invasive disease
by: Benjamin C. Hunt, et al.
Published: (2024-12-01) -
Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements.
by: Chelsie E Armbruster, et al.
Published: (2017-06-01) -
Construction of an Ordered Transposon Library for Uropathogenic Proteus mirabilis HI4320
by: Melanie M. Pearson, et al.
Published: (2022-12-01) -
Pyoderma caused by Proteus mirabilis in sheep
by: Mostafa Abdollahi, et al.
Published: (2022-11-01)