Generalized Pustular Psoriasis in Childhood: A Rare Case
Background: Generalized pustular psoriasis (GPP) rarely occurs under 10 years of age. GPP is typically characterized by an eruption of generalized pustules accompanied by systemic symptoms such as fever for several days, malaise, and anorexia. Pustules are sterile, with a size of 2-3 mm, and spread...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Indonesian |
| Published: |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga
2023-11-01
|
| Series: | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/BIKK/article/view/45284 |
| _version_ | 1797404630569713664 |
|---|---|
| author | vella Asnawi Mimi Maulida Nanda Earlia Arie Hidayati Fitri Dewi Ismida Mahda Rizki Liana Karamina Maghfirah Mikyal Bulqiah |
| author_facet | vella Asnawi Mimi Maulida Nanda Earlia Arie Hidayati Fitri Dewi Ismida Mahda Rizki Liana Karamina Maghfirah Mikyal Bulqiah |
| author_sort | vella Asnawi |
| collection | DOAJ |
| description | Background: Generalized pustular psoriasis (GPP) rarely occurs under 10 years of age. GPP is typically characterized by an eruption of generalized pustules accompanied by systemic symptoms such as fever for several days, malaise, and anorexia. Pustules are sterile, with a size of 2-3 mm, and spread over the trunk and extremities. This disease can be life-threatening; therefore, optimal therapy is required. Purpose: to report a rare case of GPP in childhood. Case: A 4-year-old girl with complaints of widespread red patches that spread to her neck, back, and hands, with red patches turning into streaks that are partially pus-filled and itchy. In almost all parts of the body, skin abnormalities were seen in the form of generalized erythematous plaques, well-defined borders, multiple pustules on the edges, and some plaques covered by thick scales and crusts. In the calculation of body surface area (BSA), the result is 44%, and in the calculation of generalized pustular psoriasis area and severity index (GPPASI), the result is 21.30. The patient was treated with combination topical therapy of 3% salicylic acid, desoximethasone cream 0.25%, momethasone cream 0.1% vaseline albume as emollients, and coal tar. Significant improvement was seen after 1 month of therapy. Discussion: GPP in children is a rare case. GPP is idiopathic and can be life-threatening. Until now, there has been no standard therapy that is considered the most effective and safe for children. Topical therapy may be an option. |
| first_indexed | 2024-03-09T02:57:48Z |
| format | Article |
| id | doaj.art-3b1e69fa2d8d48b58ffd5ea557646fa3 |
| institution | Directory Open Access Journal |
| issn | 1978-4279 2549-4082 |
| language | Indonesian |
| last_indexed | 2024-03-09T02:57:48Z |
| publishDate | 2023-11-01 |
| publisher | Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga |
| record_format | Article |
| series | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
| spelling | doaj.art-3b1e69fa2d8d48b58ffd5ea557646fa32023-12-05T01:38:26ZindDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas AirlanggaBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)1978-42792549-40822023-11-0135323123610.20473/bikk.V35.3.2023.231-23643369Generalized Pustular Psoriasis in Childhood: A Rare Casevella Asnawi0Mimi Maulida1Nanda Earlia2https://orcid.org/0000-0002-5358-1158Arie Hidayati3Fitri Dewi Ismida4Mahda Rizki Liana5https://orcid.org/0000-0003-0166-0185Karamina Maghfirah6Mikyal Bulqiah7Dermatology and Venereology Department, Medical Faculty of Universitas Syiah Kuala, Zainoel Abidin General Academic Hospital, Banda Aceh - IndonesiaDermatology and Venereology Department, Medical Faculty of Universitas Syiah Kuala, Zainoel Abidin General Academic Hospital, Banda Aceh - IndonesiaDermatology and Venereology Department, Medical Faculty of Universitas Syiah Kuala, Zainoel Abidin General Academic Hospital, Banda Aceh - IndonesiaDermatology and Venereology Department, Medical Faculty of Universitas Syiah Kuala, Zainoel Abidin General Academic Hospital, Banda Aceh - IndonesiaAnatomical Pathology Department, Medical Faculty of Universitas Syiah Kuala, Zainoel Abidin General Academic Hospital, Banda Aceh - IndonesiaMedical Faculty of Universitas Syiah Kuala, Zainoel Abidin General Academic Hospital, Banda Aceh - IndonesiaMedical faculty of Trisakti University, Jakarta - IndonesiaMedical Faculty of Universitas Syiah Kuala, Zainoel Abidin General Academic Hospital, Banda Aceh - IndonesiaBackground: Generalized pustular psoriasis (GPP) rarely occurs under 10 years of age. GPP is typically characterized by an eruption of generalized pustules accompanied by systemic symptoms such as fever for several days, malaise, and anorexia. Pustules are sterile, with a size of 2-3 mm, and spread over the trunk and extremities. This disease can be life-threatening; therefore, optimal therapy is required. Purpose: to report a rare case of GPP in childhood. Case: A 4-year-old girl with complaints of widespread red patches that spread to her neck, back, and hands, with red patches turning into streaks that are partially pus-filled and itchy. In almost all parts of the body, skin abnormalities were seen in the form of generalized erythematous plaques, well-defined borders, multiple pustules on the edges, and some plaques covered by thick scales and crusts. In the calculation of body surface area (BSA), the result is 44%, and in the calculation of generalized pustular psoriasis area and severity index (GPPASI), the result is 21.30. The patient was treated with combination topical therapy of 3% salicylic acid, desoximethasone cream 0.25%, momethasone cream 0.1% vaseline albume as emollients, and coal tar. Significant improvement was seen after 1 month of therapy. Discussion: GPP in children is a rare case. GPP is idiopathic and can be life-threatening. Until now, there has been no standard therapy that is considered the most effective and safe for children. Topical therapy may be an option.https://e-journal.unair.ac.id/BIKK/article/view/45284generalized pustular psoriasischildrenrare case |
| spellingShingle | vella Asnawi Mimi Maulida Nanda Earlia Arie Hidayati Fitri Dewi Ismida Mahda Rizki Liana Karamina Maghfirah Mikyal Bulqiah Generalized Pustular Psoriasis in Childhood: A Rare Case Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) generalized pustular psoriasis children rare case |
| title | Generalized Pustular Psoriasis in Childhood: A Rare Case |
| title_full | Generalized Pustular Psoriasis in Childhood: A Rare Case |
| title_fullStr | Generalized Pustular Psoriasis in Childhood: A Rare Case |
| title_full_unstemmed | Generalized Pustular Psoriasis in Childhood: A Rare Case |
| title_short | Generalized Pustular Psoriasis in Childhood: A Rare Case |
| title_sort | generalized pustular psoriasis in childhood a rare case |
| topic | generalized pustular psoriasis children rare case |
| url | https://e-journal.unair.ac.id/BIKK/article/view/45284 |
| work_keys_str_mv | AT vellaasnawi generalizedpustularpsoriasisinchildhoodararecase AT mimimaulida generalizedpustularpsoriasisinchildhoodararecase AT nandaearlia generalizedpustularpsoriasisinchildhoodararecase AT ariehidayati generalizedpustularpsoriasisinchildhoodararecase AT fitridewiismida generalizedpustularpsoriasisinchildhoodararecase AT mahdarizkiliana generalizedpustularpsoriasisinchildhoodararecase AT karaminamaghfirah generalizedpustularpsoriasisinchildhoodararecase AT mikyalbulqiah generalizedpustularpsoriasisinchildhoodararecase |