Nanomaterials for Cardiac Tissue Engineering
End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and car...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/21/5189 |
| _version_ | 1797548539437383680 |
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| author | Devang R. Amin Eric Sink Suguna P. Narayan Mostafa Abdel-Hafiz Luisa Mestroni Brisa Peña |
| author_facet | Devang R. Amin Eric Sink Suguna P. Narayan Mostafa Abdel-Hafiz Luisa Mestroni Brisa Peña |
| author_sort | Devang R. Amin |
| collection | DOAJ |
| description | End stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering. |
| first_indexed | 2024-03-10T15:01:58Z |
| format | Article |
| id | doaj.art-3b1fe87a1fc541ddaa6ee9e3c681d41d |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T15:01:58Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3b1fe87a1fc541ddaa6ee9e3c681d41d2023-11-20T20:07:38ZengMDPI AGMolecules1420-30492020-11-012521518910.3390/molecules25215189Nanomaterials for Cardiac Tissue EngineeringDevang R. Amin0Eric Sink1Suguna P. Narayan2Mostafa Abdel-Hafiz3Luisa Mestroni4Brisa Peña5Department of Internal Medicine, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USADepartment of Internal Medicine, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USADepartment of Pathology, University of Colorado Anschutz Medical Center, Aurora, CO 80045, USADepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, 12705 E. Montview Avenue, Suite 100, Aurora, CO 80045, USACardiovascular Institute, University of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, Aurora, CO 80045, USADepartment of Bioengineering, University of Colorado Denver, Anschutz Medical Campus, 12705 E. Montview Avenue, Suite 100, Aurora, CO 80045, USAEnd stage heart failure is a major cause of death in the US. At present, organ transplant and left-ventricular assist devices remain the only viable treatments for these patients. Cardiac tissue engineering presents the possibility of a new option. Nanomaterials such as gold nanorods (AuNRs) and carbon nanotubes (CNTs) present unique properties that are beneficial for cardiac tissue engineering approaches. In particular, these nanomaterials can modulate electrical conductivity, hardness, and roughness of bulk materials to improve tissue functionality. Moreover, they can deliver bioactive cargo to affect cell phenotypes. This review covers recent advances in the use of nanomaterials for cardiac tissue engineering.https://www.mdpi.com/1420-3049/25/21/5189cardiac tissue engineeringnanoparticlescarbon nanotubesgold nanorodscardiomyocyte regeneration |
| spellingShingle | Devang R. Amin Eric Sink Suguna P. Narayan Mostafa Abdel-Hafiz Luisa Mestroni Brisa Peña Nanomaterials for Cardiac Tissue Engineering Molecules cardiac tissue engineering nanoparticles carbon nanotubes gold nanorods cardiomyocyte regeneration |
| title | Nanomaterials for Cardiac Tissue Engineering |
| title_full | Nanomaterials for Cardiac Tissue Engineering |
| title_fullStr | Nanomaterials for Cardiac Tissue Engineering |
| title_full_unstemmed | Nanomaterials for Cardiac Tissue Engineering |
| title_short | Nanomaterials for Cardiac Tissue Engineering |
| title_sort | nanomaterials for cardiac tissue engineering |
| topic | cardiac tissue engineering nanoparticles carbon nanotubes gold nanorods cardiomyocyte regeneration |
| url | https://www.mdpi.com/1420-3049/25/21/5189 |
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