The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth.
In plants, the phytohormone auxin is a crucial regulator sustaining growth and development. At the cellular level, auxin is interpreted differentially in a tissue- and dose-dependent manner. Mechanisms of auxin signalling are partially unknown and the contribution of the AUXIN BINDING PROTEIN 1 (ABP...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-09-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2744284?pdf=render |
| _version_ | 1828860688241524736 |
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| author | Alexandre Tromas Nils Braun Philippe Muller Tatyana Khodus Ivan A Paponov Klaus Palme Karin Ljung Ji-Young Lee Philip Benfey James A H Murray Ben Scheres Catherine Perrot-Rechenmann |
| author_facet | Alexandre Tromas Nils Braun Philippe Muller Tatyana Khodus Ivan A Paponov Klaus Palme Karin Ljung Ji-Young Lee Philip Benfey James A H Murray Ben Scheres Catherine Perrot-Rechenmann |
| author_sort | Alexandre Tromas |
| collection | DOAJ |
| description | In plants, the phytohormone auxin is a crucial regulator sustaining growth and development. At the cellular level, auxin is interpreted differentially in a tissue- and dose-dependent manner. Mechanisms of auxin signalling are partially unknown and the contribution of the AUXIN BINDING PROTEIN 1 (ABP1) as an auxin receptor is still a matter of debate.Here we took advantage of the present knowledge of the root biological system to demonstrate that ABP1 is required for auxin response. The use of conditional ABP1 defective plants reveals that the protein is essential for maintenance of the root meristem and acts at least on the D-type CYCLIN/RETINOBLASTOMA pathway to control entry into the cell cycle. ABP1 affects PLETHORA gradients and confers auxin sensitivity to root cells thus defining the competence of the cells to be maintained within the meristem or to elongate. ABP1 is also implicated in the regulation of gene expression in response to auxin.Our data support that ABP1 is a key regulator for root growth and is required for auxin-mediated responses. Differential effects of ABP1 on various auxin responses support a model in which ABP1 is the major regulator for auxin action on the cell cycle and regulates auxin-mediated gene expression and cell elongation in addition to the already well known TIR1-mediated ubiquitination pathway. |
| first_indexed | 2024-12-13T02:44:01Z |
| format | Article |
| id | doaj.art-3b2202b7dbee47838e48206a78736a5f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-13T02:44:01Z |
| publishDate | 2009-09-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-3b2202b7dbee47838e48206a78736a5f2022-12-22T00:02:13ZengPublic Library of Science (PLoS)PLoS ONE1932-62032009-09-0149e664810.1371/journal.pone.0006648The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth.Alexandre TromasNils BraunPhilippe MullerTatyana KhodusIvan A PaponovKlaus PalmeKarin LjungJi-Young LeePhilip BenfeyJames A H MurrayBen ScheresCatherine Perrot-RechenmannIn plants, the phytohormone auxin is a crucial regulator sustaining growth and development. At the cellular level, auxin is interpreted differentially in a tissue- and dose-dependent manner. Mechanisms of auxin signalling are partially unknown and the contribution of the AUXIN BINDING PROTEIN 1 (ABP1) as an auxin receptor is still a matter of debate.Here we took advantage of the present knowledge of the root biological system to demonstrate that ABP1 is required for auxin response. The use of conditional ABP1 defective plants reveals that the protein is essential for maintenance of the root meristem and acts at least on the D-type CYCLIN/RETINOBLASTOMA pathway to control entry into the cell cycle. ABP1 affects PLETHORA gradients and confers auxin sensitivity to root cells thus defining the competence of the cells to be maintained within the meristem or to elongate. ABP1 is also implicated in the regulation of gene expression in response to auxin.Our data support that ABP1 is a key regulator for root growth and is required for auxin-mediated responses. Differential effects of ABP1 on various auxin responses support a model in which ABP1 is the major regulator for auxin action on the cell cycle and regulates auxin-mediated gene expression and cell elongation in addition to the already well known TIR1-mediated ubiquitination pathway.http://europepmc.org/articles/PMC2744284?pdf=render |
| spellingShingle | Alexandre Tromas Nils Braun Philippe Muller Tatyana Khodus Ivan A Paponov Klaus Palme Karin Ljung Ji-Young Lee Philip Benfey James A H Murray Ben Scheres Catherine Perrot-Rechenmann The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. PLoS ONE |
| title | The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. |
| title_full | The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. |
| title_fullStr | The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. |
| title_full_unstemmed | The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. |
| title_short | The AUXIN BINDING PROTEIN 1 is required for differential auxin responses mediating root growth. |
| title_sort | auxin binding protein 1 is required for differential auxin responses mediating root growth |
| url | http://europepmc.org/articles/PMC2744284?pdf=render |
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