Following Excitation/Inhibition Ratio Homeostasis from Synapse to EEG in Monogenetic Neurodevelopmental Disorders

Following Excitation/Inhibition Ratio Homeostasis from Synapse to EEG in Monogenetic Neurodevelopmental Disorders

Pharmacological options for neurodevelopmental disorders are limited to symptom suppressing agents that do not target underlying pathophysiological mechanisms. Studies on specific genetic disorders causing neurodevelopmental disorders have elucidated pathophysiological mechanisms to develop more rat...

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Bibliographic Details
Main Authors: Lisa Geertjens, Torben W. van Voorst, Arianne Bouman, Maaike A. van Boven, Tjitske Kleefstra, Matthijs Verhage, Klaus Linkenkaer-Hansen, Nael Nadif Kasri, L. Niels Cornelisse, Hilgo Bruining
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Genes
Subjects:
neurodevelopmental disorders
iPSC-based models
EEG
SNAREopathies
chromatinopathies
Online Access:https://www.mdpi.com/2073-4425/13/2/390

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