Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties
We herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission trans...
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MDPI AG
2016-06-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/21/6/774 |
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| author | Herbert Chiguvare Opeoluwa O. Oyedeji Reuben Matewu Olukayode Aremu Idris A. Oyemitan Adebola O. Oyedeji Benedicta N. Nkeh-Chungag Sandile P. Songca Sneha Mohan Oluwatobi S. Oluwafemi |
| author_facet | Herbert Chiguvare Opeoluwa O. Oyedeji Reuben Matewu Olukayode Aremu Idris A. Oyemitan Adebola O. Oyedeji Benedicta N. Nkeh-Chungag Sandile P. Songca Sneha Mohan Oluwatobi S. Oluwafemi |
| author_sort | Herbert Chiguvare |
| collection | DOAJ |
| description | We herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission transform microscopy (TEM) to confirm the formation of silver nanoparticles. Phytochemical screening of the ethanolic extract revealed the presence of glycosides, proteins, tannins, alkaloids, flavonoids and saponins. The absorption spectra showed that the synthesis is temperature and time dependent. The TEM analysis showed that the as-synthesised Ag-NPs are polydispersed and spherical in shape with average particle diameter of 19.95 ± 7.76 nm while the FTIR results confirmed the reduction and capping of the as-synthesised Ag-NPs by the phytochemicals present in the ethanolic extract. The analgesic study indicated that the combined effect of the plant extract and Ag-NPs is more effective in pain management than both the aspirin drug and the extract alone. |
| first_indexed | 2024-04-14T07:32:44Z |
| format | Article |
| id | doaj.art-3b2a2bf58ac14920bfe241549ed45f25 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-14T07:32:44Z |
| publishDate | 2016-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3b2a2bf58ac14920bfe241549ed45f252022-12-22T02:05:46ZengMDPI AGMolecules1420-30492016-06-0121677410.3390/molecules21060774molecules21060774Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic PropertiesHerbert Chiguvare0Opeoluwa O. Oyedeji1Reuben Matewu2Olukayode Aremu3Idris A. Oyemitan4Adebola O. Oyedeji5Benedicta N. Nkeh-Chungag6Sandile P. Songca7Sneha Mohan8Oluwatobi S. Oluwafemi9Department of Chemistry, Faculty of Science and Agriculture, University of Fort Hare, Private Bag X1314, Alice 5700, South AfricaDepartment of Chemistry, Faculty of Science and Agriculture, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa1124 Buchanan Street, Ginsburg, King William’s Town 5601, Eastern Cape, South AfricaDepartment of Physiology, Faculty of Health Sciences, Walter Sisulu University, Nelson Mandela Drive Campus, Mthatha 5117, South AfricaDepartment of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Nelson Mandela Drive Campus, P. Bag X1, Mthatha 5117, South AfricaDepartment of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Nelson Mandela Drive Campus, P. Bag X1, Mthatha 5117, South AfricaDepartment of Biological and Environmental Science Chemistry, Faculty of Natural Science, Walter Sisulu University, Nelson Mandela Drive Campus, P. BagX1, Mthatha 5117, South AfricaDepartment of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Nelson Mandela Drive Campus, P. Bag X1, Mthatha 5117, South AfricaCentre for Nanomaterials Science Research, University of Johannesburg, Johannesburg Doornfontein 2028, South AfricaCentre for Nanomaterials Science Research, University of Johannesburg, Johannesburg Doornfontein 2028, South AfricaWe herein report for the first time the synthesis and analgesic properties of silver nanoparticles (Ag-NPs) using buchu plant extract. The as-synthesised Ag-NPs at different temperatures were characterised by UV-Vis spectroscopy, Fourier transform infra-red spectroscopy (FTIR) and transmission transform microscopy (TEM) to confirm the formation of silver nanoparticles. Phytochemical screening of the ethanolic extract revealed the presence of glycosides, proteins, tannins, alkaloids, flavonoids and saponins. The absorption spectra showed that the synthesis is temperature and time dependent. The TEM analysis showed that the as-synthesised Ag-NPs are polydispersed and spherical in shape with average particle diameter of 19.95 ± 7.76 nm while the FTIR results confirmed the reduction and capping of the as-synthesised Ag-NPs by the phytochemicals present in the ethanolic extract. The analgesic study indicated that the combined effect of the plant extract and Ag-NPs is more effective in pain management than both the aspirin drug and the extract alone.http://www.mdpi.com/1420-3049/21/6/774silver nanoparticlesanalgesic activityphytochemicalsbuchu |
| spellingShingle | Herbert Chiguvare Opeoluwa O. Oyedeji Reuben Matewu Olukayode Aremu Idris A. Oyemitan Adebola O. Oyedeji Benedicta N. Nkeh-Chungag Sandile P. Songca Sneha Mohan Oluwatobi S. Oluwafemi Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties Molecules silver nanoparticles analgesic activity phytochemicals buchu |
| title | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
| title_full | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
| title_fullStr | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
| title_full_unstemmed | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
| title_short | Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties |
| title_sort | synthesis of silver nanoparticles using buchu plant extracts and their analgesic properties |
| topic | silver nanoparticles analgesic activity phytochemicals buchu |
| url | http://www.mdpi.com/1420-3049/21/6/774 |
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