Establishment of a uniform histological evaluation method for early stage osteophytes in the destabilization of the medial meniscus mouse model

Background: Osteophyte formation is attracting attention as an early-stage pathology of knee osteoarthritis (OA). Although osteophyte formation is understood as a defense response to joint instability, its role and impact on OA remain largely unknown. Many studies have been conducted using the surgi...

Full description

Bibliographic Details
Main Authors: Akihiro Jono, Yuta Yanagihara, Tomofumi Kinoshita, Masaki Takao, Yuuki Imai
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913123000766