Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps
We demonstrate a new synthetic strategy to cyclophanes containing thiophene and indole moieties via Grignard addition, Fischer indolization and ring-closing metathesis as key steps.
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Beilstein-Institut
2015-08-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.11.165 |
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author | Sambasivarao Kotha Ajay Kumar Chinnam Mukesh E. Shirbhate |
author_facet | Sambasivarao Kotha Ajay Kumar Chinnam Mukesh E. Shirbhate |
author_sort | Sambasivarao Kotha |
collection | DOAJ |
description | We demonstrate a new synthetic strategy to cyclophanes containing thiophene and indole moieties via Grignard addition, Fischer indolization and ring-closing metathesis as key steps. |
first_indexed | 2024-12-16T18:09:57Z |
format | Article |
id | doaj.art-3b2bda6a99fe4bbfb1eb62fcb08bf37c |
institution | Directory Open Access Journal |
issn | 1860-5397 |
language | English |
last_indexed | 2024-12-16T18:09:57Z |
publishDate | 2015-08-01 |
publisher | Beilstein-Institut |
record_format | Article |
series | Beilstein Journal of Organic Chemistry |
spelling | doaj.art-3b2bda6a99fe4bbfb1eb62fcb08bf37c2022-12-21T22:21:49ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972015-08-011111514151910.3762/bjoc.11.1651860-5397-11-165Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key stepsSambasivarao Kotha0Ajay Kumar Chinnam1Mukesh E. Shirbhate2Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai-400 076, India, Fax: 022-2572 7152Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai-400 076, India, Fax: 022-2572 7152Department of Chemistry, Indian Institute of Technology-Bombay, Powai, Mumbai-400 076, India, Fax: 022-2572 7152We demonstrate a new synthetic strategy to cyclophanes containing thiophene and indole moieties via Grignard addition, Fischer indolization and ring-closing metathesis as key steps.https://doi.org/10.3762/bjoc.11.165cyclophaneGrignard reactionFischer indolizationring-closing metathesis |
spellingShingle | Sambasivarao Kotha Ajay Kumar Chinnam Mukesh E. Shirbhate Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps Beilstein Journal of Organic Chemistry cyclophane Grignard reaction Fischer indolization ring-closing metathesis |
title | Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps |
title_full | Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps |
title_fullStr | Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps |
title_full_unstemmed | Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps |
title_short | Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps |
title_sort | design and synthesis of hybrid cyclophanes containing thiophene and indole units via grignard reaction fischer indolization and ring closing metathesis as key steps |
topic | cyclophane Grignard reaction Fischer indolization ring-closing metathesis |
url | https://doi.org/10.3762/bjoc.11.165 |
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