Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study
Abstract Aim We evaluated fine motor skills; precision, motor integration, manual dexterity, and upper-limb coordination according to sex and risk stratification in children with Acute Lymphoblastic Leukaemia (ALL). Methods We evaluated twenty-nine children in the maintenance phase aged 6 to 12 year...
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Pediatrics |
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| Online Access: | https://doi.org/10.1186/s12887-023-04316-3 |
| _version_ | 1797556359469727744 |
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| author | Xochiquetzalli Tejeda-Castellanos Carlos Maximiliano Sánchez-Medina Horacio Márquez-González José Luis Alaniz-Arcos Ma. Elena Ortiz-Cornejo Juliette Marie Brito-Suárez Luis Juárez-Villegas Claudia Gutiérrez-Camacho |
| author_facet | Xochiquetzalli Tejeda-Castellanos Carlos Maximiliano Sánchez-Medina Horacio Márquez-González José Luis Alaniz-Arcos Ma. Elena Ortiz-Cornejo Juliette Marie Brito-Suárez Luis Juárez-Villegas Claudia Gutiérrez-Camacho |
| author_sort | Xochiquetzalli Tejeda-Castellanos |
| collection | DOAJ |
| description | Abstract Aim We evaluated fine motor skills; precision, motor integration, manual dexterity, and upper-limb coordination according to sex and risk stratification in children with Acute Lymphoblastic Leukaemia (ALL). Methods We evaluated twenty-nine children in the maintenance phase aged 6 to 12 years with the Bruininks-Oseretsky Test of Motor Proficiency-second edition (BOT-2), and sex and age-specific norm values of BOT-2 were used to compare our results. Results We found lower scores on the upper-limb coordination subtest, p = 0.003 and on the manual coordination composite, p = 0.008, than normative values. Most boys performed “average” on both the subtests and the composites, but girls showed lower scores with a mean difference of 7.69 (95%CI; 2.24 to 3.14), p = 0.009. Girls’ scale scores on the upper-limb coordination subtest were lower than normative values, with mean difference 5.08 (95%CI; 2.35 to 7.81), p = 0.006. The mean standard score difference in high-risk patients was lower than normative on the manual coordination composite, 8.18 (95%CI; 2.26 to 14.1), p = 0.015. High-risk children also performed below the BOT-2 normative on manual dexterity 2.82 (95%CI; 0.14 to 5.78), p = 0.035 and upper limb coordination subtest 4.10 (95%CI; 1.13 to 7.05), p = 0.028. We found a decrease in fine motor precision in children with a higher BMI, rho= -0.87, p = 0.056 and a negative correlation between older age and lower manual dexterity, r= -0.41 p = 0.026; however, we did not find any correlation with the weeks in the maintenance phase. Conclusions Fine motor impairments are common in children with ALL in the maintenance phase; it is important to identify these impairments to early rehabilitation. |
| first_indexed | 2024-03-10T17:01:43Z |
| format | Article |
| id | doaj.art-3b2dd62736604c3b85f505c9c7cd0e62 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-03-10T17:01:43Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-3b2dd62736604c3b85f505c9c7cd0e622023-11-20T10:56:47ZengBMCBMC Pediatrics1471-24312023-10-012311810.1186/s12887-023-04316-3Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional studyXochiquetzalli Tejeda-Castellanos0Carlos Maximiliano Sánchez-Medina1Horacio Márquez-González2José Luis Alaniz-Arcos3Ma. Elena Ortiz-Cornejo4Juliette Marie Brito-Suárez5Luis Juárez-Villegas6Claudia Gutiérrez-Camacho7Physiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de MéxicoPhysiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de MéxicoResearch Department, Hospital Infantil de México Federico GómezPhysiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de MéxicoPhysiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de MéxicoPhysiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de MéxicoHaematology and oncology department of the Hospital Infantil de Mexico, Federico GómezPhysiotherapy Research Unit, Faculty of Medicine, Universidad Nacional Autónoma de MéxicoAbstract Aim We evaluated fine motor skills; precision, motor integration, manual dexterity, and upper-limb coordination according to sex and risk stratification in children with Acute Lymphoblastic Leukaemia (ALL). Methods We evaluated twenty-nine children in the maintenance phase aged 6 to 12 years with the Bruininks-Oseretsky Test of Motor Proficiency-second edition (BOT-2), and sex and age-specific norm values of BOT-2 were used to compare our results. Results We found lower scores on the upper-limb coordination subtest, p = 0.003 and on the manual coordination composite, p = 0.008, than normative values. Most boys performed “average” on both the subtests and the composites, but girls showed lower scores with a mean difference of 7.69 (95%CI; 2.24 to 3.14), p = 0.009. Girls’ scale scores on the upper-limb coordination subtest were lower than normative values, with mean difference 5.08 (95%CI; 2.35 to 7.81), p = 0.006. The mean standard score difference in high-risk patients was lower than normative on the manual coordination composite, 8.18 (95%CI; 2.26 to 14.1), p = 0.015. High-risk children also performed below the BOT-2 normative on manual dexterity 2.82 (95%CI; 0.14 to 5.78), p = 0.035 and upper limb coordination subtest 4.10 (95%CI; 1.13 to 7.05), p = 0.028. We found a decrease in fine motor precision in children with a higher BMI, rho= -0.87, p = 0.056 and a negative correlation between older age and lower manual dexterity, r= -0.41 p = 0.026; however, we did not find any correlation with the weeks in the maintenance phase. Conclusions Fine motor impairments are common in children with ALL in the maintenance phase; it is important to identify these impairments to early rehabilitation.https://doi.org/10.1186/s12887-023-04316-3Acute Lymphoblastic LeukaemiaChild development disorderCoordination impairmentFine motor skillsLeukaemiaVincristine |
| spellingShingle | Xochiquetzalli Tejeda-Castellanos Carlos Maximiliano Sánchez-Medina Horacio Márquez-González José Luis Alaniz-Arcos Ma. Elena Ortiz-Cornejo Juliette Marie Brito-Suárez Luis Juárez-Villegas Claudia Gutiérrez-Camacho Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study BMC Pediatrics Acute Lymphoblastic Leukaemia Child development disorder Coordination impairment Fine motor skills Leukaemia Vincristine |
| title | Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study |
| title_full | Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study |
| title_fullStr | Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study |
| title_full_unstemmed | Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study |
| title_short | Impairments in fine motor skills in children with Acute Lymphoblastic Leukaemia. A cross-sectional study |
| title_sort | impairments in fine motor skills in children with acute lymphoblastic leukaemia a cross sectional study |
| topic | Acute Lymphoblastic Leukaemia Child development disorder Coordination impairment Fine motor skills Leukaemia Vincristine |
| url | https://doi.org/10.1186/s12887-023-04316-3 |
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