Unique Features of the Immune Response in BTBR Mice

Unique Features of the Immune Response in BTBR Mice

Inflammation plays a considerable role in the pathogenesis of many diseases, including neurodegenerative and psychiatric ones. Elucidation of the specific features of an immune response in various model organisms, and studying the relation of these features with the behavioral phenotype, can improve...

Full description

Bibliographic Details
Main Authors:	Anastasia Mutovina, Kseniya Ayriyants, Eva Mezhlumyan, Yulia Ryabushkina, Ekaterina Litvinova, Natalia Bondar, Julia Khantakova, Vasiliy Reshetnikov
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	International Journal of Molecular Sciences
Subjects:	Poly I:C LPS neuroinflammation BTBR
Online Access:	https://www.mdpi.com/1422-0067/23/24/15577

Similar Items

Molecular Abnormalities in BTBR Mice and Their Relevance to Schizophrenia and Autism Spectrum Disorders: An Overview of Transcriptomic and Proteomic Studies
by: Polina Kisaretova, et al.
Published: (2023-01-01)

Th17 Cells, Glucocorticoid Resistance, and Depression
by: Julia N. Khantakova, et al.
Published: (2023-11-01)

Human amniotic epithelial cell transplantation promotes neurogenesis and ameliorates social deficits in BTBR mice
by: Ruiyu Zhang, et al.
Published: (2019-05-01)

GW4064 Alters Gut Microbiota Composition and Counteracts Autism-Associated Behaviors in BTBR T+tf/J Mice
by: Jiayin Liu, et al.
Published: (2022-06-01)

Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders
by: Martina Tallarico, et al.
Published: (2023-04-01)

Prebiotic, Probiotic, and Synbiotic Consumption Alter Behavioral Variables and Intestinal Permeability and Microbiota in BTBR Mice
by: Jodi E. Nettleton, et al.
Published: (2021-08-01)

Neuronal correlates of asocial behavior in a BTBR T+Itpr3tf/J mouse model of autism
by: Ksenia Zuzanna Meyza, et al.
Published: (2015-08-01)

Comparative gene expression analysis of two mouse models of autism:transcriptome profiling of the BTBR and En2-/- hippocampus
by: Giovanni Provenzano, et al.
Published: (2016-08-01)

Altered meningeal immunity contributing to the autism-like behavior of BTBR T+ Itpr3tf/J mice
by: Mohammad Nizam Uddin, et al.
Published: (2022-12-01)

Metformin Administration During Early Postnatal Life Rescues Autistic-Like Behaviors in the BTBR T+ Itpr3tf/J Mouse Model of Autism
by: Lian Wang, et al.
Published: (2018-11-01)

Hippocampal transcriptomic and proteomic alterations in the BTBR mouse model of autism spectrum disorder
by: Caitlin M Daimon, et al.
Published: (2015-11-01)

Brain-Derived Neurotrophic Factor (BDNF) in Mechanisms of Autistic-like Behavior in BTBR Mice: Crosstalk with the Dopaminergic Brain System
by: Tatiana Ilchibaeva, et al.
Published: (2023-05-01)

Behavioral, Anti-Inflammatory, and Neuroprotective Effects of a Novel FPR2 Agonist in Two Mouse Models of Autism
by: Claudia Cristiano, et al.
Published: (2022-01-01)

Cadmium Exposure Is Associated with Behavioral Deficits and Neuroimmune Dysfunction in BTBR T<sup>+</sup> Itpr3tf/J Mice
by: Mohammed M. Alanazi, et al.
Published: (2023-03-01)

Once induced, it lasts for a long time: the structural and molecular signatures associated with depressive-like behavior after neonatal immune activation
by: Julia N. Khantakova, et al.
Published: (2022-12-01)

General Anesthesia During Neurodevelopment Reduces Autistic Behavior in Adult BTBR Mice, a Murine Model of Autism
by: Jianchen Cui, et al.
Published: (2021-11-01)

5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism
by: Khaled Alhosaini, et al.
Published: (2021-02-01)

The Exposure to Lead (Pb) Exacerbates Immunological Abnormalities in BTBR T<sup>+</sup> Itpr<sup>3tf</sup>/J Mice through the Regulation of Signaling Pathways Relevant to T Cells
by: Mohammed A. Assiri, et al.
Published: (2023-11-01)

Meta-Inflammation and De Novo Lipogenesis Markers Are Involved in Metabolic Associated Fatty Liver Disease Progression in BTBR ob/ob Mice
by: Lucas Opazo-Ríos, et al.
Published: (2022-04-01)

Comparative analysis of exosomal miRNAs derived from lipopolysaccharide and polyinosinic-polycytidylic acid-stimulated chicken macrophage cell line
by: Yeojin Hong, et al.
Published: (2022-11-01)

Selection and Verification of Reference Genes for Gene Expression Studies in Different Cell Lines of Golden Pompano (<i>Trachinotus ovatus</i>)
by: Na Zhao, et al.
Published: (2022-12-01)

The NOD1 and NOD2 in mandarinfish (Siniperca chuatsi): molecular characterization, tissue distribution, and expression analysis
by: Tiantian Gu, et al.
Published: (2018-08-01)

Enhancement of Short-Term Memory by Methyl-6-(Phenylethynyl)-Pyridine in the BTBR T+tf/J Mouse Model of Autism Spectrum Disorder
by: Haijie Yang, et al.
Published: (2015-03-01)

Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder
by: Melina Matthiesen, et al.
Published: (2023-05-01)

Simultaneous Blockade of Histamine H<sub>3</sub> Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism
by: Nermin Eissa, et al.
Published: (2020-08-01)

Immune Transcriptional Response in Head Kidney Primary Cell Cultures Isolated from the Three Most Important Species in Chilean Salmonids Aquaculture
by: Daniela P. Nualart, et al.
Published: (2023-06-01)

Spleen Transcriptome Profiling Reveals Divergent Immune Responses to LPS and Poly (I:C) Challenge in the Yellow Drum (<i>Nibea albiflora</i>)
by: Xiang Zhao, et al.
Published: (2023-04-01)

Precision-cut rat placental slices as a model to study sex-dependent inflammatory response to LPS and Poly I:C
by: Kasin Yadunandam Anandam, et al.
Published: (2022-12-01)

A comprehensive approach to modeling maternal immune activation in rodents
by: Morgan C. Bucknor, et al.
Published: (2022-12-01)

The effects of urolithin A on poly I:C-induced microglial activation
by: Yakum Benard Mingo, et al.
Published: (2024-03-01)

Perinatal exposure to synergistic multiple stressors leads to cellular and behavioral deficits mimicking Schizophrenia-like pathology
by: Tiyasha Sarkar, et al.
Published: (2022-03-01)

Neuronal changes and cognitive deficits in a multi-hit rat model following cumulative impact of early life stressors
by: Tiyasha Sarkar, et al.
Published: (2020-09-01)

Weighted Gene Co-Expression Network Analysis Based on Stimulation by Lipopolysaccharides and Polyinosinic:polycytidylic Acid Provides a Core Set of Genes for Understanding Hemolymph Immune Response Mechanisms of <i>Amphioctopus fangsiao</i>
by: Yongjie Wang, et al.
Published: (2023-12-01)

Cloning, characterization and expression analysis of caspase-8 genes from the golden pompano (Trachinotus ovatus)
by: Fan Da, et al.
Published: (2022-12-01)

Optimización de un protocolo de inducción de genes inmunitarios (Dicer-2 – Argonaute-2) del camarón blanco Litopenaeus vannamei para su establecimiento como biomarcadores potenciales en programas de mejoramiento genético.
by: Tayron Vera, et al.
Published: (2014-12-01)

Cathelicidin-Related Antimicrobial Peptide Negatively Regulates Bacterial Endotoxin-Induced Glial Activation
by: Anup Bhusal, et al.
Published: (2022-12-01)

Aflatoxin B<sub>1</sub> Exposure Aggravates Neurobehavioral Deficits and Immune Dysfunctions of Th1, Th9, Th17, Th22, and T Regulatory Cell-Related Transcription Factor Signaling in the BTBR T<sup>+</sup>Itpr3<sup>tf</sup>/J Mouse Model of Autism
by: Mohammad Y. Alwetaid, et al.
Published: (2023-10-01)

Differential Expression of Endogenous Retroviruses and Inflammatory Mediators in Female and Male Offspring in a Mouse Model of Maternal Immune Activation
by: Chiara Cipriani, et al.
Published: (2022-11-01)

Epigenetic histone acetylation modulating prenatal Poly I:C induced neuroinflammation in the prefrontal cortex of rats: a study in a maternal immune activation model
by: Yueqing Su, et al.
Published: (2022-11-01)

The effects of mango leaf extract during adolescence and adulthood in a rat model of schizophrenia
by: Jose Antonio Garcia-Partida, et al.
Published: (2022-07-01)