Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative study
The use of thiazide, thiazide-like and loop diuretics in patients with hypertension is widely discussed. So far, there have been few direct comparative studies of different classes of diuretics in hypertension. The randomized, comparative, open DOVERIE study (efficacy and safety of Diuver in combina...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2014-12-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/682 |
| _version_ | 1797841891674292224 |
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| author | OP Shevchenko EE Averin VA Vygodin |
| author_facet | OP Shevchenko EE Averin VA Vygodin |
| author_sort | OP Shevchenko |
| collection | DOAJ |
| description | The use of thiazide, thiazide-like and loop diuretics in patients with hypertension is widely discussed. So far, there have been few direct comparative studies of different classes of diuretics in hypertension. The randomized, comparative, open DOVERIE study (efficacy and safety of Diuver in combination therapy in hypertensive patients in outpatient setting) found that the antihypertensive effects and safety of torasemide and indapamide are not significantly different. Adding torasemide either to monotherapy with ACEI/ARB II or as substitute for hydrochlorothiazide in combination therapy with ACEI/ARB II + HCTZ resulted in a further significant decrease in blood pressure and allowed to reach target BP in a majority of patients. Therapy with torasemide was not associated with any increase in heart rate, significant changes in potassium levels, uric acid and glucose. |
| first_indexed | 2024-04-09T16:39:55Z |
| format | Article |
| id | doaj.art-3b36cad3b5d848a29d68125772b2e3ce |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:39:55Z |
| publishDate | 2014-12-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-3b36cad3b5d848a29d68125772b2e3ce2023-04-23T06:56:45ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902014-12-01012182410.21518/2079-701X-2014-12-18-24682Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative studyOP Shevchenko0EE Averin1VA Vygodin2Pirogov Russian National Research Medical University, MoscowPirogov Russian National Research Medical University, MoscowNational Research Center for Preventive Medicine, MoscowThe use of thiazide, thiazide-like and loop diuretics in patients with hypertension is widely discussed. So far, there have been few direct comparative studies of different classes of diuretics in hypertension. The randomized, comparative, open DOVERIE study (efficacy and safety of Diuver in combination therapy in hypertensive patients in outpatient setting) found that the antihypertensive effects and safety of torasemide and indapamide are not significantly different. Adding torasemide either to monotherapy with ACEI/ARB II or as substitute for hydrochlorothiazide in combination therapy with ACEI/ARB II + HCTZ resulted in a further significant decrease in blood pressure and allowed to reach target BP in a majority of patients. Therapy with torasemide was not associated with any increase in heart rate, significant changes in potassium levels, uric acid and glucose.https://www.med-sovet.pro/jour/article/view/682артериальная гипертонияторасемидиндапамидгидрохлоротиазидкомбинированная терапияhypertensiontorasemideindapamidehydrochlorothiazidecombination therapy |
| spellingShingle | OP Shevchenko EE Averin VA Vygodin Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative study Медицинский совет артериальная гипертония торасемид индапамид гидрохлоротиазид комбинированная терапия hypertension torasemide indapamide hydrochlorothiazide combination therapy |
| title | Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative study |
| title_full | Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative study |
| title_fullStr | Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative study |
| title_full_unstemmed | Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative study |
| title_short | Diuretics in the treatment of patients with arterial hypertension: results of the DOVERIE comparative study |
| title_sort | diuretics in the treatment of patients with arterial hypertension results of the doverie comparative study |
| topic | артериальная гипертония торасемид индапамид гидрохлоротиазид комбинированная терапия hypertension torasemide indapamide hydrochlorothiazide combination therapy |
| url | https://www.med-sovet.pro/jour/article/view/682 |
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