Association of DNA methylation signatures with premature ageing and cardiovascular death in patients with end-stage kidney disease: a pilot epigenome-wide association study

Association of DNA methylation signatures with premature ageing and cardiovascular death in patients with end-stage kidney disease: a pilot epigenome-wide association study

Patients with end-stage kidney disease (ESKD) display features of premature aging. There is strong evidence that changes in DNA methylation (DNAm) contribute to age-related pathologies; however, little is known about their association with premature aging and cardiovascular mortality in patients wit...

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Bibliographic Details
Main Authors: Keiichi Sumida, Khyobeni Mozhui, Xiaoyu Liang, Yamini Mallisetty, Zhongji Han, Csaba P. Kovesdy
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
aging
cardiovascular disease
dna methylation
epigenetics clock
end-stage kidney disease
mortality
Online Access:http://dx.doi.org/10.1080/15592294.2023.2214394

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