Molecular basis of AR and STK11 genes associated pathogenesis via AMPK pathway and adipocytokine signalling pathway in the development of metabolic disorders in PCOS women

Molecular basis of AR and STK11 genes associated pathogenesis via AMPK pathway and adipocytokine signalling pathway in the development of metabolic disorders in PCOS women

Abstract Background One of the most common hormonal disorders in women of reproductive age is polycystic ovary syndrome (PCOS). In recent years, it has been found that insulin resistance is a common metabolic abnormality in women with PCOS and leads to an elevated risk of type 2 diabetes mellitus. T...

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Bibliographic Details
Main Authors: Pavan Gollapalli, N. Suchetha Kumari, Praveenkumar Shetty, Tamizh Selvan Gnanasekaran
Format: Article
Language:English
Published: SpringerOpen 2022-02-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
PCOS
GEO data set
Gene interaction network
DEGs
Online Access:https://doi.org/10.1186/s43088-022-00200-8

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