Upregulation of programmed death ligand-1 in tumor-associated macrophages affects chemotherapeutic response in ovarian cancer cells.
To better understand the mechanism of chemoresistance in ovarian cancer cells, we aimed to investigate the influence of macrophages on the tumor cell response to carboplatin and identify the genes associated with chemoresistance. We mimicked the tumor microenvironment (TME) using a co-culture techni...
Main Authors: | Yong Soo Jang, Tae Wan Kim, Jae Sung Ryu, Hye Jeong Kong, Si Hyeong Jang, Gye Hyun Nam, Jae Hoon Kim, Seob Jeon |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0277285 |
Similar Items
-
Upregulation of programmed death ligand-1 in tumor-associated macrophages affects chemotherapeutic response in ovarian cancer cells
by: Yong Soo Jang, et al.
Published: (2023-01-01) -
Circulating Exosomal miR-1290 for Diagnosis of Epithelial Ovarian Cancer
by: Hyeji Jeon, et al.
Published: (2022-01-01) -
The Effects of Chemotherapeutics on the Ovarian Cancer Microenvironment
by: Mark A. Eckert, et al.
Published: (2021-06-01) -
A Bayesian Network Meta-Analysis of First-Line Treatments for Non-Small Cell Lung Cancer with High Programmed Death Ligand-1 Expression
by: Jung Han Kim, et al.
Published: (2022-03-01) -
Inhibition of Programmed Death Receptor-1/Programmed Death Ligand-1 Interactions by Ginsenoside Metabolites
by: Nam-Hui Yim, et al.
Published: (2020-04-01)