Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig

SARS-CoV-2 uses ACE2 as the entry receptor. Here, the authors show that an ACE2-Ig fusion protein inhibits entry of virus pseudotyped with the SARS-CoV-2 spike protein, show differential binding kinetics of SARS-CoV and SARSCoV-2 spike proteins to ACE2, and determine pharmakocinetic parameters of AC...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Changhai Lei, Kewen Qian, Tian Li, Sheng Zhang, Wenyan Fu, Min Ding, Shi Hu
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2020-04-01
Ráidu:Nature Communications
Liŋkkat:https://doi.org/10.1038/s41467-020-16048-4