Carboplatin: molecular mechanisms of action associated with chemoresistance

Carboplatin is a derivative of cisplatin; it has a similar mechanism of action, but differs in terms of structure and toxicity. It was approved by the FDA in the 1980s and since then it has been widely used in the treatment of several tumor types. This agent is characterized by its ability to genera...

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Bibliographic Details
Main Authors: Graziele Fonseca de Sousa, Samarina Rodrigues Wlodarczyk, Gisele Monteiro
Format: Article
Language:English
Published: Universidade de São Paulo 2014-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400693&lng=en&tlng=en