The role of barrier membranes in guided bone regeneration; A review

The Guided Bone Regeneration (GBR) treatment concept advocates that regeneration of osseous defects is predictably attainable via the application of occlusive membranes, which mechanically exclude non-osteogenic cell populations from the surrounding soft tissues, thereby allowing osteogenic cell pop...

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Main Authors: Farzane Jabari, Behzad Houshmand, Saeed Hesaraki
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2018-12-01
Series:Journal of Dental Medicine
Subjects:
Online Access:http://jdm.tums.ac.ir/browse.php?a_code=A-10-235-5&slc_lang=en&sid=1
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author Farzane Jabari
Behzad Houshmand
Saeed Hesaraki
author_facet Farzane Jabari
Behzad Houshmand
Saeed Hesaraki
author_sort Farzane Jabari
collection DOAJ
description The Guided Bone Regeneration (GBR) treatment concept advocates that regeneration of osseous defects is predictably attainable via the application of occlusive membranes, which mechanically exclude non-osteogenic cell populations from the surrounding soft tissues, thereby allowing osteogenic cell populations originating from the parent bone to inhabit the osseous wound. The use of membrane to exclude non-osteogenic cells, is a key principle of guided bone regeneration. A large number of membranes have been evaluated in clinical and experimental studies. The object of this study was to review the literature regarding guided bone regeneration and all types of membranes that were used in this technique. 72 articles between the years 1968 through the 2016 from PubMed, Medline and Google Scholar using the related keywords, were selected. Finally, we concluded that the modification of mechanical and physico-chemical properties of membranes could improve the process of new bone growth. However, determination of the exact role of membrane porosity in this process, still needs to be clarified. Optimization the chemical composition of membrane with the focus and attention to obstructive property and bioactivity, is an important point in this research field. Various factors such as flexibility, mechanical strength and degradation rate determine the type of membrane used for bone tissue regeneration.
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spelling doaj.art-3b420ca4d74044c5b47f0c88abd354f22022-12-21T18:15:26ZfasTehran University of Medical SciencesJournal of Dental Medicine1024-641X2008-24442018-12-01313198207The role of barrier membranes in guided bone regeneration; A reviewFarzane Jabari0Behzad Houshmand1Saeed Hesaraki2 Ph.D Candidate in Biomedical Engineering (Biomaterial), Research Department of Nano-Technology and Advanced Materials, Materials and Energy Research Center (MERC), Karaj, Iran Professor, Department of Periodontology School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran Associate Professor of Research, Research Department of Nano-Technology and Advanced Materials, Materials and Energy Research Center (MERC), Karaj, Iran The Guided Bone Regeneration (GBR) treatment concept advocates that regeneration of osseous defects is predictably attainable via the application of occlusive membranes, which mechanically exclude non-osteogenic cell populations from the surrounding soft tissues, thereby allowing osteogenic cell populations originating from the parent bone to inhabit the osseous wound. The use of membrane to exclude non-osteogenic cells, is a key principle of guided bone regeneration. A large number of membranes have been evaluated in clinical and experimental studies. The object of this study was to review the literature regarding guided bone regeneration and all types of membranes that were used in this technique. 72 articles between the years 1968 through the 2016 from PubMed, Medline and Google Scholar using the related keywords, were selected. Finally, we concluded that the modification of mechanical and physico-chemical properties of membranes could improve the process of new bone growth. However, determination of the exact role of membrane porosity in this process, still needs to be clarified. Optimization the chemical composition of membrane with the focus and attention to obstructive property and bioactivity, is an important point in this research field. Various factors such as flexibility, mechanical strength and degradation rate determine the type of membrane used for bone tissue regeneration.http://jdm.tums.ac.ir/browse.php?a_code=A-10-235-5&slc_lang=en&sid=1Biocompatible materialsMembraneBone regeneration
spellingShingle Farzane Jabari
Behzad Houshmand
Saeed Hesaraki
The role of barrier membranes in guided bone regeneration; A review
Journal of Dental Medicine
Biocompatible materials
Membrane
Bone regeneration
title The role of barrier membranes in guided bone regeneration; A review
title_full The role of barrier membranes in guided bone regeneration; A review
title_fullStr The role of barrier membranes in guided bone regeneration; A review
title_full_unstemmed The role of barrier membranes in guided bone regeneration; A review
title_short The role of barrier membranes in guided bone regeneration; A review
title_sort role of barrier membranes in guided bone regeneration a review
topic Biocompatible materials
Membrane
Bone regeneration
url http://jdm.tums.ac.ir/browse.php?a_code=A-10-235-5&slc_lang=en&sid=1
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