The halo sign: HRCT findings in 85 patients
ABSTRACT Objective: The halo sign consists of an area of ground-glass opacity surrounding pulmonary lesions on chest CT scans. We compared immunocompetent and immunosuppressed patients in terms of halo sign features and sought to identify those of greatest diagnostic value. Methods: This was a ret...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Pneumologia e Tisiologia
|
| Series: | Jornal Brasileiro de Pneumologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132016000600435&lng=en&tlng=en |
| _version_ | 1811265186857746432 |
|---|---|
| author | Giordano Rafael Tronco Alves Edson Marchiori Klaus Irion Carlos Schuler Nin Guilherme Watte Alessandro Comarú Pasqualotto Luiz Carlos Severo Bruno Hochhegger |
| author_facet | Giordano Rafael Tronco Alves Edson Marchiori Klaus Irion Carlos Schuler Nin Guilherme Watte Alessandro Comarú Pasqualotto Luiz Carlos Severo Bruno Hochhegger |
| author_sort | Giordano Rafael Tronco Alves |
| collection | DOAJ |
| description | ABSTRACT Objective: The halo sign consists of an area of ground-glass opacity surrounding pulmonary lesions on chest CT scans. We compared immunocompetent and immunosuppressed patients in terms of halo sign features and sought to identify those of greatest diagnostic value. Methods: This was a retrospective study of CT scans performed at any of seven centers between January of 2011 and May of 2015. Patients were classified according to their immune status. Two thoracic radiologists reviewed the scans in order to determine the number of lesions, as well as their distribution, size, and contour, together with halo thickness and any other associated findings. Results: Of the 85 patients evaluated, 53 were immunocompetent and 32 were immunosuppressed. Of the 53 immunocompetent patients, 34 (64%) were diagnosed with primary neoplasm. Of the 32 immunosuppressed patients, 25 (78%) were diagnosed with aspergillosis. Multiple and randomly distributed lesions were more common in the immunosuppressed patients than in the immunocompetent patients (p < 0.001 for both). Halo thickness was found to be greater in the immunosuppressed patients (p < 0.05). Conclusions: Etiologies of the halo sign differ markedly between immunocompetent and immunosuppressed patients. Although thicker halos are more likely to occur in patients with infectious diseases, the number and distribution of lesions should also be taken into account when evaluating patients presenting with the halo sign. |
| first_indexed | 2024-04-12T20:17:53Z |
| format | Article |
| id | doaj.art-3b464a23c6e44468a7f222bac1c1c6c1 |
| institution | Directory Open Access Journal |
| issn | 1806-3756 |
| language | English |
| last_indexed | 2024-04-12T20:17:53Z |
| publisher | Sociedade Brasileira de Pneumologia e Tisiologia |
| record_format | Article |
| series | Jornal Brasileiro de Pneumologia |
| spelling | doaj.art-3b464a23c6e44468a7f222bac1c1c6c12022-12-22T03:18:03ZengSociedade Brasileira de Pneumologia e TisiologiaJornal Brasileiro de Pneumologia1806-375642643543910.1590/s1806-37562015000000029S1806-37132016000600435The halo sign: HRCT findings in 85 patientsGiordano Rafael Tronco AlvesEdson MarchioriKlaus IrionCarlos Schuler NinGuilherme WatteAlessandro Comarú PasqualottoLuiz Carlos SeveroBruno HochheggerABSTRACT Objective: The halo sign consists of an area of ground-glass opacity surrounding pulmonary lesions on chest CT scans. We compared immunocompetent and immunosuppressed patients in terms of halo sign features and sought to identify those of greatest diagnostic value. Methods: This was a retrospective study of CT scans performed at any of seven centers between January of 2011 and May of 2015. Patients were classified according to their immune status. Two thoracic radiologists reviewed the scans in order to determine the number of lesions, as well as their distribution, size, and contour, together with halo thickness and any other associated findings. Results: Of the 85 patients evaluated, 53 were immunocompetent and 32 were immunosuppressed. Of the 53 immunocompetent patients, 34 (64%) were diagnosed with primary neoplasm. Of the 32 immunosuppressed patients, 25 (78%) were diagnosed with aspergillosis. Multiple and randomly distributed lesions were more common in the immunosuppressed patients than in the immunocompetent patients (p < 0.001 for both). Halo thickness was found to be greater in the immunosuppressed patients (p < 0.05). Conclusions: Etiologies of the halo sign differ markedly between immunocompetent and immunosuppressed patients. Although thicker halos are more likely to occur in patients with infectious diseases, the number and distribution of lesions should also be taken into account when evaluating patients presenting with the halo sign.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132016000600435&lng=en&tlng=enTomografia computadorizada por raios XAspergiloseNeoplasias pulmonares |
| spellingShingle | Giordano Rafael Tronco Alves Edson Marchiori Klaus Irion Carlos Schuler Nin Guilherme Watte Alessandro Comarú Pasqualotto Luiz Carlos Severo Bruno Hochhegger The halo sign: HRCT findings in 85 patients Jornal Brasileiro de Pneumologia Tomografia computadorizada por raios X Aspergilose Neoplasias pulmonares |
| title | The halo sign: HRCT findings in 85 patients |
| title_full | The halo sign: HRCT findings in 85 patients |
| title_fullStr | The halo sign: HRCT findings in 85 patients |
| title_full_unstemmed | The halo sign: HRCT findings in 85 patients |
| title_short | The halo sign: HRCT findings in 85 patients |
| title_sort | halo sign hrct findings in 85 patients |
| topic | Tomografia computadorizada por raios X Aspergilose Neoplasias pulmonares |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132016000600435&lng=en&tlng=en |
| work_keys_str_mv | AT giordanorafaeltroncoalves thehalosignhrctfindingsin85patients AT edsonmarchiori thehalosignhrctfindingsin85patients AT klausirion thehalosignhrctfindingsin85patients AT carlosschulernin thehalosignhrctfindingsin85patients AT guilhermewatte thehalosignhrctfindingsin85patients AT alessandrocomarupasqualotto thehalosignhrctfindingsin85patients AT luizcarlossevero thehalosignhrctfindingsin85patients AT brunohochhegger thehalosignhrctfindingsin85patients AT giordanorafaeltroncoalves halosignhrctfindingsin85patients AT edsonmarchiori halosignhrctfindingsin85patients AT klausirion halosignhrctfindingsin85patients AT carlosschulernin halosignhrctfindingsin85patients AT guilhermewatte halosignhrctfindingsin85patients AT alessandrocomarupasqualotto halosignhrctfindingsin85patients AT luizcarlossevero halosignhrctfindingsin85patients AT brunohochhegger halosignhrctfindingsin85patients |