Diverse Galactooligosaccharides Differentially Reduce LPS-Induced Inflammation in Macrophages

Diverse Galactooligosaccharides Differentially Reduce LPS-Induced Inflammation in Macrophages

The effects of natural and synthetic galactooligosaccharides (GOS) on inflammation were explored by investigating the structure-activity relationship between the degree of GOS polymerization and in vitro anti-inflammatory activity, together with the potential underlying mechanism of their anti-infla...

Full description

Bibliographic Details
Main Authors:	Congcong Sun, Bifang Hao, Daorui Pang, Qian Li, Erna Li, Qiong Yang, Yuxiao Zou, Sentai Liao, Fan Liu
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Foods
Subjects:	galactooligosaccharide RAW264.7 cells lipopolysaccharide (LPS) anti-inflammatory activity TLR4/NF-κB signaling pathway
Online Access:	https://www.mdpi.com/2304-8158/11/24/3973

Similar Items

Effects of propofol on lipopolysaccharide-induced expression and release of HMGB1 in macrophages
by: T. Wang, et al.
Published: (2015-04-01)

Phenethylferulate as a natural inhibitor of inflammation in LPS-stimulated RAW 264.7 macrophages: focus on NF-κB, Akt and MAPK signaling pathways
by: Zhongjie Yan, et al.
Published: (2023-11-01)

Isodorsmanin A Prevents Inflammatory Response in LPS-Stimulated Macrophages by Inhibiting the JNK and NF-κB Signaling Pathways
by: You Chul Chung, et al.
Published: (2023-02-01)

Optimization of Preparation of Galactooligosaccharides by β-Galactosidase Using Response Surface Methodology
by: Congcong SUN, et al.
Published: (2022-11-01)

Anti-oxidative and anti-inflammatory activities of the ethanol extract of edible flower from Chimonanthus praecox
by: Yuan Kang, et al.
Published: (2022-09-01)

Xanthatin Alleviates LPS-Induced Inflammatory Response in RAW264.7 Macrophages by Inhibiting NF-κB, MAPK and STATs Activation
by: Yuanqi Liu, et al.
Published: (2022-07-01)

Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7)
by: Wahyu Widowati, et al.
Published: (2021-12-01)

Inhibition of NF-кB Expression in LPS-Induced RAW264.7 Macrophage Cells by a Thiazolidinone Derivative (TZD-OCH2 CH3 )
by: Farahnaz Hasanzadeh, et al.
Published: (2021-12-01)

Anti-inflammatory effect of Momordica grosvenori Swingle extract through suppressed LPS-induced upregulation of iNOS and COX-2 in murine macrophages
by: Min-Hsiung Pan, et al.
Published: (2009-04-01)

Luteolin exerted less inhibitory effect on macrophage activation induced by Astragalus polysaccharide than by lipopolysaccharide
by: Zhi-Peng Li, et al.
Published: (2017-10-01)

DMSO Alleviates LPS-Induced Inflammatory Responses in RAW264.7 Macrophages by Inhibiting NF-κB and MAPK Activation
by: Hyunju Han, et al.
Published: (2023-06-01)

Effects of β-Glucan on the Release of Nitric Oxide by Macrophages Stimulated with Lipopolysaccharide
by: E. Y. Choi, et al.
Published: (2016-11-01)

Anti-inflammatory effects of Glycine tabacina extract in LPS-stimulated macrophages and collagen-induced arthritis mice
by: Yanbei Tu, et al.
Published: (2019-11-01)

Synthesis and Biological Properties of Pyranocoumarin Derivatives as Potent Anti-Inflammatory Agents
by: Su Ji Min, et al.
Published: (2023-06-01)

Effect of Inotodiol on LPS-induced Injury of RAW264.7 Cells
by: Yanbin ZHU, et al.
Published: (2023-10-01)

<i>Mesosphaerum suaveolens</i> Essential Oil Attenuates Inflammatory Response and Oxidative Stress in LPS-Stimulated RAW 264.7 Macrophages by Regulating NF-κB Signaling Pathway
by: Omprakash Mohanta, et al.
Published: (2023-08-01)

Lipopolysaccharide induced MAP kinase activation in RAW 264.7 cells attenuated by cerium oxide nanoparticles
by: Vellaisamy Selvaraj, et al.
Published: (2015-09-01)

Mechanisms of TQ-6, a Novel Ruthenium-Derivative Compound, against Lipopolysaccharide-Induced In Vitro Macrophage Activation and Liver Injury in Experimental Mice: The Crucial Role of p38 MAPK and NF-κB Signaling
by: Chih-Hsuan Hsia, et al.
Published: (2018-11-01)

Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages
by: Erna Sulistyowati, et al.
Published: (2018-08-01)

Octominin Inhibits LPS-Induced Chemokine and Pro-inflammatory Cytokine Secretion from RAW 264.7 Macrophages via Blocking TLRs/NF-κB Signal Transduction
by: K. K. Asanka Sanjeewa, et al.
Published: (2020-03-01)

Ethanol extract separated from Sargassum horneri (Turner) abate LPS-induced inflammation in RAW 264.7 macrophages
by: K. K. Asanka Sanjeewa, et al.
Published: (2019-02-01)

Activation of Nrf2/HO-1 by Peptide YD1 Attenuates Inflammatory Symptoms through Suppression of TLR4/MYyD88/NF-κB Signaling Cascade
by: Md Saifur Rahman, et al.
Published: (2021-05-01)

Structural Alternation in Heat Shock Proteins of Activated Macrophages
by: Wenhao Zhang, et al.
Published: (2021-12-01)

Comparison of the in vitro Anti-Inflammatory Effect of Cannabidiol to Dexamethasone
by: Wang Y, et al.
Published: (2022-09-01)

Anti-inflammatory effect of ethanolic extract from <it>Myagropsis myagroides</it> on murine macrophages and mouse ear edema
by: Joung Eun-Ji, et al.
Published: (2012-10-01)

Gambogic acid inhibits LPS-induced macrophage pro-inflammatory cytokine production mainly through suppression of the p38 pathway
by: Ma Jianjun, et al.
Published: (2018-07-01)

Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways
by: Shuping Sun, et al.
Published: (2019-12-01)

The pepsinolytic hydrolysate from Johnius belengerii frame inhibited LPS-stimulated production of pro-inflammatory mediators via the inactivating of JNK and NF-κB pathways in RAW 264.7 macrophages
by: Seong-Yeong Heo, et al.
Published: (2018-05-01)

Ameliorative Effect of Areca Nut Polyphenols on Adverse Effects Induced by Lipopolysaccharides in RAW264.7 Cells
by: Luyan Zou, et al.
Published: (2024-03-01)

Syzygium cumini seed attenuates LPS induced inflammatory response in murine macrophage cell line RAW264.7 through NF-κB translocation
by: H.P. Syama, et al.
Published: (2018-05-01)

Phenolic mediated anti-inflammatory properties of a maple syrup extract in RAW 264.7 murine macrophages
by: Pragati P. Nahar, et al.
Published: (2014-01-01)

Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-κB signaling pathways
by: Ching-Shu Lai, et al.
Published: (2011-07-01)

The Anti-Inflammatory Mechanism of Flaxseed Linusorbs on Lipopolysaccharide-Induced RAW 264.7 Macrophages by Modulating TLR4/NF-κB/MAPK Pathway
by: Jialong Li, et al.
Published: (2023-06-01)

Ethanol extract of Chondracanthus tenellus (Harvey) Hommersand attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB, MAPKs, and PI3K/Akt signaling pathways
by: Da Hye Kwon, et al.
Published: (2021-01-01)

The Immunomodulatory Effects of Active Ingredients From Nigella sativa in RAW264.7 Cells Through NF-κB/MAPK Signaling Pathways
by: Jinfeng Wei, et al.
Published: (2022-05-01)

Inhibitory Effect of N,N-Didesmethylgrossularine-1 on Inflammatory Cytokine Production in Lipopolysaccharide-Stimulated RAW 264.7 Cells
by: Remy E. P. Mangindaan, et al.
Published: (2009-11-01)

<i>Neocinnamomum caudatum</i> Essential Oil Ameliorates Lipopolysaccharide-Induced Inflammation and Oxidative Stress in RAW 264.7 Cells by Inhibiting NF-κB Activation and ROS Production
by: Sudipta Jena, et al.
Published: (2022-11-01)

Porcine β-Defensin 114: Creating a Dichotomous Response to Inflammation
by: Guoqi Su, et al.
Published: (2024-01-01)

Anti-Inflammatory Effect of Neoechinulin A from the Marine Fungus Eurotium sp. SF-5989 through the Suppression of NF-кB and p38 MAPK Pathways in Lipopolysaccharide-Stimulated RAW264.7 Macrophages
by: Kyoung-Su Kim, et al.
Published: (2013-10-01)

Anti-Inflammatory Mechanisms of Koreanaside A, a Lignan Isolated from the Flower of <i>Forsythia koreana</i>, against LPS-Induced Macrophage Activation and DSS-Induced Colitis Mice: The Crucial Role of AP-1, NF-κB, and JAK/STAT Signaling
by: Tae-Woo Kim, et al.
Published: (2019-09-01)