SNORD89 promotes stemness phenotype of ovarian cancer cells by regulating Notch1-c-Myc pathway

SNORD89 promotes stemness phenotype of ovarian cancer cells by regulating Notch1-c-Myc pathway

Abstract Background Ovarian cancer is the leading cause of death in gynecological cancer. Cancer stem cells (CSCs) contribute to the occurrence, progression and resistance. Small nucleolar RNAs (SnoRNAs), a class of small molecule non-coding RNA, involve in the cancer cell stemness and tumorigenesis...

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Main Authors: Wenjing Zhu, Jumin Niu, Miao He, Liwen Zhang, Xuemei Lv, Fangxiao Liu, Longyang Jiang, Jing Zhang, Zhaojin Yu, Lin Zhao, Jia Bi, Yuanyuan Yan, Qian Wei, Hong Huo, Yue Fan, Yuzong Chen, Jian Ding, Minjie Wei
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Translational Medicine
Subjects:
Ovarian cancer stem cells
TCGA
SNORNAs
SNORD89
Online Access:http://link.springer.com/article/10.1186/s12967-019-2005-1

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