Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods
A diverse range of predatory marine gastropods produce toxins, yet most of these molecules remain uncharacterized. Conus species have received the most attention from researchers, leading to several conopeptides reaching clinical trials. This review aims to summarize what is known about bioactive co...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-04-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1660-3397/16/4/118 |
| _version_ | 1828154182363774976 |
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| author | Ashlin H. Turner David J. Craik Quentin Kaas Christina I. Schroeder |
| author_facet | Ashlin H. Turner David J. Craik Quentin Kaas Christina I. Schroeder |
| author_sort | Ashlin H. Turner |
| collection | DOAJ |
| description | A diverse range of predatory marine gastropods produce toxins, yet most of these molecules remain uncharacterized. Conus species have received the most attention from researchers, leading to several conopeptides reaching clinical trials. This review aims to summarize what is known about bioactive compounds isolated from species of neglected marine gastropods, especially in the Turridae, Terebridae, Babyloniidae, Muricidae, Buccinidae, Colubrariidae, Nassariidae, Cassidae, and Ranellidae families. Multiple species have been reported to contain bioactive compounds with potential toxic activity, but most of these compounds have not been characterized or even clearly identified. The bioactive properties and potential applications of echotoxins and related porins from the Ranellidae family are discussed in more detail. Finally, the review concludes with a call for research on understudied species. |
| first_indexed | 2024-04-11T22:35:42Z |
| format | Article |
| id | doaj.art-3b55a64e1981415a851df355d71e7736 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T22:35:42Z |
| publishDate | 2018-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-3b55a64e1981415a851df355d71e77362022-12-22T03:59:13ZengMDPI AGMarine Drugs1660-33972018-04-0116411810.3390/md16040118md16040118Bioactive Compounds Isolated from Neglected Predatory Marine GastropodsAshlin H. Turner0David J. Craik1Quentin Kaas2Christina I. Schroeder3Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Qld, AustraliaInstitute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Qld, AustraliaInstitute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Qld, AustraliaInstitute for Molecular Bioscience, The University of Queensland, Brisbane, 4072, Qld, AustraliaA diverse range of predatory marine gastropods produce toxins, yet most of these molecules remain uncharacterized. Conus species have received the most attention from researchers, leading to several conopeptides reaching clinical trials. This review aims to summarize what is known about bioactive compounds isolated from species of neglected marine gastropods, especially in the Turridae, Terebridae, Babyloniidae, Muricidae, Buccinidae, Colubrariidae, Nassariidae, Cassidae, and Ranellidae families. Multiple species have been reported to contain bioactive compounds with potential toxic activity, but most of these compounds have not been characterized or even clearly identified. The bioactive properties and potential applications of echotoxins and related porins from the Ranellidae family are discussed in more detail. Finally, the review concludes with a call for research on understudied species.http://www.mdpi.com/1660-3397/16/4/118toxinsmarine gastropodssalivary glandspeptidesRanellidaeechotoxins |
| spellingShingle | Ashlin H. Turner David J. Craik Quentin Kaas Christina I. Schroeder Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods Marine Drugs toxins marine gastropods salivary glands peptides Ranellidae echotoxins |
| title | Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods |
| title_full | Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods |
| title_fullStr | Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods |
| title_full_unstemmed | Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods |
| title_short | Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods |
| title_sort | bioactive compounds isolated from neglected predatory marine gastropods |
| topic | toxins marine gastropods salivary glands peptides Ranellidae echotoxins |
| url | http://www.mdpi.com/1660-3397/16/4/118 |
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