Retinoic Acid signalling and the control of meiotic entry in the human fetal gonad.
The development of mammalian fetal germ cells along oogenic or spermatogenic fate trajectories is dictated by signals from the surrounding gonadal environment. Germ cells in the fetal testis enter mitotic arrest, whilst those in the fetal ovary undergo sex-specific entry into meiosis, the initiation...
Main Authors: | Andrew J Childs, Gillian Cowan, Hazel L Kinnell, Richard A Anderson, Philippa T K Saunders |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3108594?pdf=render |
Similar Items
-
Regulation of meiotic entry and gonadal sex differentiation in the human: normal and disrupted signaling
by: Jørgensen Anne, et al.
Published: (2014-08-01) -
Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads
by: Laura Bellutti, et al.
Published: (2019-09-01) -
Retinoic acid-stimulated ERK1/2 pathway regulates meiotic initiation in cultured fetal germ cells.
by: Sung-Min Kim, et al.
Published: (2019-01-01) -
A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.
by: Jing He, et al.
Published: (2013-01-01) -
Correction: A Developmental Stage-Specific Switch from DAZL to BOLL Occurs during Fetal Oogenesis in Humans, but Not Mice.
by: Jing He, et al.
Published: (2013-01-01)