The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysis
ObjectiveTo evaluate the efficiency of laparoscopic surgery in treating recurrent liver tumors vs. conventional open surgery.MethodsDatabase searching was conducted in PubMed, the Cochrane Library and EMBASE. Rev Man 5.3 software and Stata 13.0 software were applied in statistical analyses.ResultsA...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1042458/full |
| _version_ | 1797959955638124544 |
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| author | Tian-Run Lv Hai-Jie Hu Wen-Jie Ma Ya-Fei Hu Yu-Shi Dai Fu-Yu Li |
| author_facet | Tian-Run Lv Hai-Jie Hu Wen-Jie Ma Ya-Fei Hu Yu-Shi Dai Fu-Yu Li |
| author_sort | Tian-Run Lv |
| collection | DOAJ |
| description | ObjectiveTo evaluate the efficiency of laparoscopic surgery in treating recurrent liver tumors vs. conventional open surgery.MethodsDatabase searching was conducted in PubMed, the Cochrane Library and EMBASE. Rev Man 5.3 software and Stata 13.0 software were applied in statistical analyses.ResultsA total of fourteen studies were finally included with 1,284 patients receiving LRH and 2,254 with ORH. LRH was associated with less intraoperative hemorrhage, a higher R0 resection rate, a lower incidence of Pringle Maneuver, a lower incidence of postoperative morbidities, a better overall survival and an enhanced postoperative recovery vs. ORH. Patients receiving LRH shared similar operative time, tumor number and disease-free survival as those with ORH. However, tumor size was relatively larger in patients receiving ORH and major hepatectomy, anatomic hepatectomy were rarely performed in patients with LRH. Additional analyses between LRH and laparoscopic primary hepatectomy revealed less intraoperative blood loss in patients with LRH.ConclusionLRH is safe and feasible with more favorable peri-operative outcomes and faster postoperative recovery. However, it is only applicable for some highly-selected cases not requiring complex surgical procedures. Future larger well-designed studies are expected for further validation. |
| first_indexed | 2024-04-11T00:38:58Z |
| format | Article |
| id | doaj.art-3b59382c9bf84719bc945bbe1bb25d48 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-11T00:38:58Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-3b59382c9bf84719bc945bbe1bb25d482023-01-06T09:30:07ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-01-01910.3389/fsurg.2022.10424581042458The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysisTian-Run LvHai-Jie HuWen-Jie MaYa-Fei HuYu-Shi DaiFu-Yu LiObjectiveTo evaluate the efficiency of laparoscopic surgery in treating recurrent liver tumors vs. conventional open surgery.MethodsDatabase searching was conducted in PubMed, the Cochrane Library and EMBASE. Rev Man 5.3 software and Stata 13.0 software were applied in statistical analyses.ResultsA total of fourteen studies were finally included with 1,284 patients receiving LRH and 2,254 with ORH. LRH was associated with less intraoperative hemorrhage, a higher R0 resection rate, a lower incidence of Pringle Maneuver, a lower incidence of postoperative morbidities, a better overall survival and an enhanced postoperative recovery vs. ORH. Patients receiving LRH shared similar operative time, tumor number and disease-free survival as those with ORH. However, tumor size was relatively larger in patients receiving ORH and major hepatectomy, anatomic hepatectomy were rarely performed in patients with LRH. Additional analyses between LRH and laparoscopic primary hepatectomy revealed less intraoperative blood loss in patients with LRH.ConclusionLRH is safe and feasible with more favorable peri-operative outcomes and faster postoperative recovery. However, it is only applicable for some highly-selected cases not requiring complex surgical procedures. Future larger well-designed studies are expected for further validation.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1042458/fulllaparoscopichepatectomyrecurrentliver resectionminimally invasive |
| spellingShingle | Tian-Run Lv Hai-Jie Hu Wen-Jie Ma Ya-Fei Hu Yu-Shi Dai Fu-Yu Li The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysis Frontiers in Surgery laparoscopic hepatectomy recurrent liver resection minimally invasive |
| title | The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysis |
| title_full | The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysis |
| title_fullStr | The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysis |
| title_full_unstemmed | The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysis |
| title_short | The role of laparoscopic surgery in the surgical management of recurrent liver malignancies: A systematic review and meta-analysis |
| title_sort | role of laparoscopic surgery in the surgical management of recurrent liver malignancies a systematic review and meta analysis |
| topic | laparoscopic hepatectomy recurrent liver resection minimally invasive |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1042458/full |
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