Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system

This paper proposes a new method of generating pulsatile flow using non-pulsating pumps (NPP) without modulating the rotation speed of the pump rotor. At the initial stage, this method was proposed for NPP-based cardiopulmonary bypass (CPB) systems. The method is based on parallel connection to the...

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Main Authors: A. S. Buchnev, A. P. Kuleshov, A. A. Drobyshev, G. P. Itkin
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2019-10-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/1065
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author A. S. Buchnev
A. P. Kuleshov
A. A. Drobyshev
G. P. Itkin
author_facet A. S. Buchnev
A. P. Kuleshov
A. A. Drobyshev
G. P. Itkin
author_sort A. S. Buchnev
collection DOAJ
description This paper proposes a new method of generating pulsatile flow using non-pulsating pumps (NPP) without modulating the rotation speed of the pump rotor. At the initial stage, this method was proposed for NPP-based cardiopulmonary bypass (CPB) systems. The method is based on parallel connection to the NPP shunt (input-output) on which a controlled valve is installed. This valve ensures periodically clamps and opens the shunt partially. A comparative evaluation of the operation of pumps with and without a pulsator was done on a hydrodynamic bench with simulation of heart failure (HF) conditions. The pump-shunt system was connected according to the “veinartery” CPB scheme under copulsation mode. Rotaflow (Maquet Inc.) was used as the NPP. For a comparative assessment of the hemodynamic efficiency of the method, the following were used: aortic pulsatility index Ip, energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). The indices in the pulsating mode compared with the non-pulsating mode increased: Ip by 3 times, EEP index by 3.76% and SHE index increased by 4 times. Results show that the proposed method of generating a pulsating flow is effective.
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spelling doaj.art-3b5a03aa1a6d420f863efc249c1992492023-03-13T10:37:25ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912019-10-01213697510.15825/1995-1191-2019-3-69-75805Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass systemA. S. Buchnev0A. P. Kuleshov1A. A. Drobyshev2G. P. Itkin3V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation; Moscow Institute of Physics and TechnologyThis paper proposes a new method of generating pulsatile flow using non-pulsating pumps (NPP) without modulating the rotation speed of the pump rotor. At the initial stage, this method was proposed for NPP-based cardiopulmonary bypass (CPB) systems. The method is based on parallel connection to the NPP shunt (input-output) on which a controlled valve is installed. This valve ensures periodically clamps and opens the shunt partially. A comparative evaluation of the operation of pumps with and without a pulsator was done on a hydrodynamic bench with simulation of heart failure (HF) conditions. The pump-shunt system was connected according to the “veinartery” CPB scheme under copulsation mode. Rotaflow (Maquet Inc.) was used as the NPP. For a comparative assessment of the hemodynamic efficiency of the method, the following were used: aortic pulsatility index Ip, energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). The indices in the pulsating mode compared with the non-pulsating mode increased: Ip by 3 times, EEP index by 3.76% and SHE index increased by 4 times. Results show that the proposed method of generating a pulsating flow is effective.https://journal.transpl.ru/vtio/article/view/1065cardiopulmonary bypasscontinuous flowpulsatile flowhydrodynamic standshuntcontrolled valve
spellingShingle A. S. Buchnev
A. P. Kuleshov
A. A. Drobyshev
G. P. Itkin
Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system
Vestnik Transplantologii i Iskusstvennyh Organov
cardiopulmonary bypass
continuous flow
pulsatile flow
hydrodynamic stand
shunt
controlled valve
title Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system
title_full Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system
title_fullStr Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system
title_full_unstemmed Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system
title_short Hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system
title_sort hemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass system
topic cardiopulmonary bypass
continuous flow
pulsatile flow
hydrodynamic stand
shunt
controlled valve
url https://journal.transpl.ru/vtio/article/view/1065
work_keys_str_mv AT asbuchnev hemodynamicevaluationofanewpulsatileflowgenerationmethodincardiopulmonarybypasssystem
AT apkuleshov hemodynamicevaluationofanewpulsatileflowgenerationmethodincardiopulmonarybypasssystem
AT aadrobyshev hemodynamicevaluationofanewpulsatileflowgenerationmethodincardiopulmonarybypasssystem
AT gpitkin hemodynamicevaluationofanewpulsatileflowgenerationmethodincardiopulmonarybypasssystem