Dose-dependent in vitro inhibition of rabbit corneal matrix metalloproteinases by an extract of Pothomorphe umbellata after alkali injury

Dose-dependent in vitro inhibition of rabbit corneal matrix metalloproteinases by an extract of Pothomorphe umbellata after alkali injury

The in vitro ability of Pothomorphe umbellata ethanolic crude extract to inhibit matrix metalloproteinase (MMP) in normal cornea and in cornea after alkali injury was demonstrated. Corneas of albino rabbits were injured with 1 N NaOH for 20 s. After 48 h the corneas were excised, homogenized and ana...

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Bibliographic Details
Main Authors:	L.F.M. Barros, P.S.M. Barros, C.D. Röpke, V.V. Silva, T.C.H. Sawada, S.B.M. Barros, R. Belfort Jr.
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2007-08-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Cornea Alkali injury Metalloproteinases Pothomorphe umbellata
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800014

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