A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context
There is a controversial concept among many studies whether neonatal seizures are risk factors for neonatal death and/or neurodevelopment impairments (in case of newborn survivors). Multiple factors have been analyzed in literature, including perinatal factors, etiology factors, seizures characteris...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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EduSoft publishing
2018-05-01
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| Series: | Brain: Broad Research in Artificial Intelligence and Neuroscience |
| Subjects: | |
| Online Access: | https://www.edusoft.ro/brain/index.php/brain/article/view/810/939 |
| _version_ | 1797985810702663680 |
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| author | Ionela Maniu George Maniu Cristina Dospinescu Gabriela Visa |
| author_facet | Ionela Maniu George Maniu Cristina Dospinescu Gabriela Visa |
| author_sort | Ionela Maniu |
| collection | DOAJ |
| description | There is a controversial concept among many studies whether neonatal seizures are risk factors for neonatal death and/or neurodevelopment impairments (in case of newborn survivors). Multiple factors have been analyzed in literature, including perinatal factors, etiology factors, seizures characteristics factors, investigations findings factors, therapy-related factors. This paper aims to review the characteristics and the application context of different computational models developed for identifying both the risk factor of morbidity (epilepsy, cerebral palsy, development disability or their combination) and the mortality outcome after neonatal seizures. Consequently, we determined the groups of main risk factors using factor analysis. The vast majority of identified models are logistic regression models, but also decision tree models. In the literature, there is a large variation in establishing the risk factors determining poor or favorable outcome after a neonatal seizure, with similarities and inconsistencies. These findings could be a consequence of different approaches regarding inclusion criteria, methodologies used to identify seizure, seizures definition or description, analysis using computational models. |
| first_indexed | 2024-04-11T07:24:08Z |
| format | Article |
| id | doaj.art-3b5b27715f4449f7b40a1d4a715ae7a8 |
| institution | Directory Open Access Journal |
| issn | 2067-3957 |
| language | English |
| last_indexed | 2024-04-11T07:24:08Z |
| publishDate | 2018-05-01 |
| publisher | EduSoft publishing |
| record_format | Article |
| series | Brain: Broad Research in Artificial Intelligence and Neuroscience |
| spelling | doaj.art-3b5b27715f4449f7b40a1d4a715ae7a82022-12-22T04:37:07ZengEduSoft publishingBrain: Broad Research in Artificial Intelligence and Neuroscience2067-39572018-05-019295103A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure ContextIonela Maniu0George Maniu1Cristina Dospinescu2Gabriela Visa3Research and Telemedicine Center in Neurological Diseases in Children, Pediatric Clinical Hospital, Sibiu, Romania 3 George Barițiu, 550178, Tel. 0269 230 250 Department of Mathematics and Computer Science, “Lucian Blaga” University, Sibiu, Romania Bulevardul Victoriei 10, Sibiu 550024, Tel.: 0269 216 062 ionela.maniu@yahoo.roDepartment of Mathematics and Computer Science, “Lucian Blaga” University , Sibiu, Romania 10 Bulevardul Victoriei, 550024, Tel.: 0269 216 062 george.maniu@ulbsibiu.roResearch and Telemedicine Center in Neurological Diseases in Children, Pediatric Clinical Hospital, Sibiu, Romania 3 George Barițiu, 550178, Tel. 0269 230 250 cristinadospinescu@yahoo.comResearch and Telemedicine Center in Neurological Diseases in Children, Pediatric Clinical Hospital, Sibiu, Romania 3 George Barițiu, 550178, Tel. 0269 230 250 gabiap@yahoo.comThere is a controversial concept among many studies whether neonatal seizures are risk factors for neonatal death and/or neurodevelopment impairments (in case of newborn survivors). Multiple factors have been analyzed in literature, including perinatal factors, etiology factors, seizures characteristics factors, investigations findings factors, therapy-related factors. This paper aims to review the characteristics and the application context of different computational models developed for identifying both the risk factor of morbidity (epilepsy, cerebral palsy, development disability or their combination) and the mortality outcome after neonatal seizures. Consequently, we determined the groups of main risk factors using factor analysis. The vast majority of identified models are logistic regression models, but also decision tree models. In the literature, there is a large variation in establishing the risk factors determining poor or favorable outcome after a neonatal seizure, with similarities and inconsistencies. These findings could be a consequence of different approaches regarding inclusion criteria, methodologies used to identify seizure, seizures definition or description, analysis using computational models.https://www.edusoft.ro/brain/index.php/brain/article/view/810/939neonatal seizuresrisk factorsepilepsymortalitylogistic regressiondecision tree |
| spellingShingle | Ionela Maniu George Maniu Cristina Dospinescu Gabriela Visa A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context Brain: Broad Research in Artificial Intelligence and Neuroscience neonatal seizures risk factors epilepsy mortality logistic regression decision tree |
| title | A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context |
| title_full | A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context |
| title_fullStr | A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context |
| title_full_unstemmed | A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context |
| title_short | A Factor Analysis Model for Dimension Reduction of Outcome Factors in Neonatal Seizure Context |
| title_sort | factor analysis model for dimension reduction of outcome factors in neonatal seizure context |
| topic | neonatal seizures risk factors epilepsy mortality logistic regression decision tree |
| url | https://www.edusoft.ro/brain/index.php/brain/article/view/810/939 |
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