Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat Breeds
The current study was designed to determine the emergence of resistance among gastrointestinal roundworms of native goats against renowned synthetic antinematicidals such as fenbendazole, avermectin and levamisole. To meet the survey requirements, six commercial goat farms, located in Sothern and We...
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| Format: | Article |
| Language: | English |
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Salahaddin University-Erbil
2020-09-01
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| Series: | Zanco Journal of Pure and Applied Sciences |
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| Online Access: | https://zancojournals.su.edu.krd/index.php/JPAS/article/view/3467 |
| _version_ | 1811283243644747776 |
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| author | Kareem Khoshnow Hamad Fikry Qadir |
| author_facet | Kareem Khoshnow Hamad Fikry Qadir |
| author_sort | Kareem Khoshnow Hamad |
| collection | DOAJ |
| description | The current study was designed to determine the emergence of resistance among gastrointestinal roundworms of native goats against renowned synthetic antinematicidals such as fenbendazole, avermectin and levamisole. To meet the survey requirements, six commercial goat farms, located in Sothern and Western Erbil province-Kurdistan region of Iraq, were chosen after performing qualitative parasitological assays. The study was executed from September to end of November, 2019. From each farm, 30 adult goats were haphazardly divided into two groups, a group (n=15) for treatment and other group (n=15) served as control. The faecal egg count reduction test (FECRT) and egg hatch assay (EHA) have disclosed emergence of resistance against fenbendazole. According to RESO Computer Program, the estimated FECR% in farms 1 and 2 were 70.72 and 79.55, whilst the lower confidence intervals 95% were 63 and 73.8 respectively. The LC50 value of fenbendazole after conducting EHA, calculated through probit analysis, was estimated to be 2.11 μg ml ־¹ (range 1.47-2.34). Regarding avermectin, the computed FECR% in farms 3 and 4 were 93.92 and 92.98, while the lower confidence intervals 95% were 92.91 and 90.7 respectively, which signified the presence of suspicion about prevalence of resistance against avermectin. For levamisole, the calculated FECR% in farms 5 and 6 were 95.99 and 96.38, whilst the lower confidence intervals 95% were 95.1 and 95.7 respectively. Consequently, the parasitic nematodes were susceptible to this synthetic chemotherapeutic in the region |
| first_indexed | 2024-04-13T02:08:01Z |
| format | Article |
| id | doaj.art-3b60938319d046f4b50a32e013257887 |
| institution | Directory Open Access Journal |
| issn | 2218-0230 2412-3986 |
| language | English |
| last_indexed | 2024-04-13T02:08:01Z |
| publishDate | 2020-09-01 |
| publisher | Salahaddin University-Erbil |
| record_format | Article |
| series | Zanco Journal of Pure and Applied Sciences |
| spelling | doaj.art-3b60938319d046f4b50a32e0132578872022-12-22T03:07:24ZengSalahaddin University-ErbilZanco Journal of Pure and Applied Sciences2218-02302412-39862020-09-0132410.21271/ZJPAS.32.4.12Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat BreedsKareem Khoshnow Hamad0Fikry Qadir1Department of Biology, College of Science, Salahaddin University- Erbil, Kurdistan Region of IraqDepartment of Biology, College of Science, Salahaddin University- Erbil, Kurdistan Region of IraqThe current study was designed to determine the emergence of resistance among gastrointestinal roundworms of native goats against renowned synthetic antinematicidals such as fenbendazole, avermectin and levamisole. To meet the survey requirements, six commercial goat farms, located in Sothern and Western Erbil province-Kurdistan region of Iraq, were chosen after performing qualitative parasitological assays. The study was executed from September to end of November, 2019. From each farm, 30 adult goats were haphazardly divided into two groups, a group (n=15) for treatment and other group (n=15) served as control. The faecal egg count reduction test (FECRT) and egg hatch assay (EHA) have disclosed emergence of resistance against fenbendazole. According to RESO Computer Program, the estimated FECR% in farms 1 and 2 were 70.72 and 79.55, whilst the lower confidence intervals 95% were 63 and 73.8 respectively. The LC50 value of fenbendazole after conducting EHA, calculated through probit analysis, was estimated to be 2.11 μg ml ־¹ (range 1.47-2.34). Regarding avermectin, the computed FECR% in farms 3 and 4 were 93.92 and 92.98, while the lower confidence intervals 95% were 92.91 and 90.7 respectively, which signified the presence of suspicion about prevalence of resistance against avermectin. For levamisole, the calculated FECR% in farms 5 and 6 were 95.99 and 96.38, whilst the lower confidence intervals 95% were 95.1 and 95.7 respectively. Consequently, the parasitic nematodes were susceptible to this synthetic chemotherapeutic in the regionhttps://zancojournals.su.edu.krd/index.php/JPAS/article/view/3467indigenous caprinealimentary tract nematodessynthetic dewormersantinematicidal resistanceerbil province |
| spellingShingle | Kareem Khoshnow Hamad Fikry Qadir Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat Breeds Zanco Journal of Pure and Applied Sciences indigenous caprine alimentary tract nematodes synthetic dewormers antinematicidal resistance erbil province |
| title | Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat Breeds |
| title_full | Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat Breeds |
| title_fullStr | Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat Breeds |
| title_full_unstemmed | Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat Breeds |
| title_short | Rampancy of Antinematicidal Resistance Among Gastrointestinal Nematodes in Kurdish Goat Breeds |
| title_sort | rampancy of antinematicidal resistance among gastrointestinal nematodes in kurdish goat breeds |
| topic | indigenous caprine alimentary tract nematodes synthetic dewormers antinematicidal resistance erbil province |
| url | https://zancojournals.su.edu.krd/index.php/JPAS/article/view/3467 |
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