Investigation of cytotoxic effects of Eugenia caryophyllus (Clove)
Objectives: Eugenia caryophyllus has been used as a traditional medicinal herb for thousands of years. It is used as an analgesic for tooth and toothache with the effect of eugenol substance included in clove. Clove is used at toothpaste and some mouthwash. The aim of this study was determined of in...
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| Format: | Article |
| Language: | English |
| Published: |
Cumhuriyet University
2018-10-01
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| Series: | Cumhuriyet Dental Journal |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/555581 |
| Summary: | Objectives:
Eugenia caryophyllus has been used as a
traditional medicinal herb for thousands of years. It is used as an analgesic for tooth and toothache
with the effect of eugenol substance included in clove. Clove is used at toothpaste and some mouthwash. The
aim of this study was determined of in vitro cytotoxic effects Eugenia caryophyllus on fibroblast
cells.
Materials
and Methods: Cytotoxic
activity of Eugenia caryophyllus was evaluated
using XTT assay.
Results: In the present study, toxicity of
clove that is used as a pain reliever in dentistry has examined on L929 cells. Eugenia
caryophyllus were
incubated at 24 and 48 hours. The IC50 values of Eugenia caryophyllus (Clove) were found 57,92 ± 0,98 µg/mL in 24 h,
37,97 ± 0,74 µg/mL in 48h.
Conclusions: The acceptable level of cytotoxicity associated with Eugenia caryophyllus requires further evaluation to be used |
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| ISSN: | 1302-5805 2146-2852 |