Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer
Autoimmune pancreatitis (AIP) can be difficult to distinguish from pancreatic cancer. We report a case of histopathologically proven AIP mimicking neuroendocrine tumor (NET) or pancreatic cancer in a 53-year-old man. He was referred to our hospital for further evaluation of a pancreatic mass detecte...
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Format: | Article |
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Karger Publishers
2012-01-01
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Series: | Case Reports in Gastroenterology |
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Online Access: | http://www.karger.com/Article/FullText/336199 |
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author | Shinji Onda Tomoyoshi Okamoto Masaru Kanehira Shuichi Fujioka Tohru Harada Hiroshi Hano Masaharu Fukunaga Katsuhiko Yanaga |
author_facet | Shinji Onda Tomoyoshi Okamoto Masaru Kanehira Shuichi Fujioka Tohru Harada Hiroshi Hano Masaharu Fukunaga Katsuhiko Yanaga |
author_sort | Shinji Onda |
collection | DOAJ |
description | Autoimmune pancreatitis (AIP) can be difficult to distinguish from pancreatic cancer. We report a case of histopathologically proven AIP mimicking neuroendocrine tumor (NET) or pancreatic cancer in a 53-year-old man. He was referred to our hospital for further evaluation of a pancreatic mass detected on ultrasonography at a medical check-up. Abdominal ultrasonography showed a 15-mm hypoechoic mass located in the pancreatic body. Computed tomography revealed a tumor without any contrast enhancement, and magnetic resonance imaging demonstrated the mass to be hyperintense on diffusion-weighted image. Endoscopic retrograde cholangiopancreatography revealed slight dilatation of a branch of the pancreatic duct without stricture of the main pancreatic duct. The common bile duct seemed intact. Under suspicion of a non-functioning NET or malignant neoplasm, laparotomy was performed. At laparotomy, an elastic firm and well-circumscribed mass was found suggestive of a non-functioning NET, thus enucleation was performed. Histopathologically, the lesion corresponded to AIP. |
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issn | 1662-0631 |
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spelling | doaj.art-3b641b234a6f4d4a85652a1582a1c39c2022-12-22T00:53:56ZengKarger PublishersCase Reports in Gastroenterology1662-06312012-01-0161404610.1159/000336199336199Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic CancerShinji OndaTomoyoshi OkamotoMasaru KanehiraShuichi FujiokaTohru HaradaHiroshi HanoMasaharu FukunagaKatsuhiko YanagaAutoimmune pancreatitis (AIP) can be difficult to distinguish from pancreatic cancer. We report a case of histopathologically proven AIP mimicking neuroendocrine tumor (NET) or pancreatic cancer in a 53-year-old man. He was referred to our hospital for further evaluation of a pancreatic mass detected on ultrasonography at a medical check-up. Abdominal ultrasonography showed a 15-mm hypoechoic mass located in the pancreatic body. Computed tomography revealed a tumor without any contrast enhancement, and magnetic resonance imaging demonstrated the mass to be hyperintense on diffusion-weighted image. Endoscopic retrograde cholangiopancreatography revealed slight dilatation of a branch of the pancreatic duct without stricture of the main pancreatic duct. The common bile duct seemed intact. Under suspicion of a non-functioning NET or malignant neoplasm, laparotomy was performed. At laparotomy, an elastic firm and well-circumscribed mass was found suggestive of a non-functioning NET, thus enucleation was performed. Histopathologically, the lesion corresponded to AIP.http://www.karger.com/Article/FullText/336199Fine-needle biopsyIgG4Differential diagnosisEndoscopic ultrasonography |
spellingShingle | Shinji Onda Tomoyoshi Okamoto Masaru Kanehira Shuichi Fujioka Tohru Harada Hiroshi Hano Masaharu Fukunaga Katsuhiko Yanaga Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer Case Reports in Gastroenterology Fine-needle biopsy IgG4 Differential diagnosis Endoscopic ultrasonography |
title | Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer |
title_full | Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer |
title_fullStr | Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer |
title_full_unstemmed | Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer |
title_short | Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer |
title_sort | histopathologically proven autoimmune pancreatitis mimicking neuroendocrine tumor or pancreatic cancer |
topic | Fine-needle biopsy IgG4 Differential diagnosis Endoscopic ultrasonography |
url | http://www.karger.com/Article/FullText/336199 |
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