Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer

Autoimmune pancreatitis (AIP) can be difficult to distinguish from pancreatic cancer. We report a case of histopathologically proven AIP mimicking neuroendocrine tumor (NET) or pancreatic cancer in a 53-year-old man. He was referred to our hospital for further evaluation of a pancreatic mass detecte...

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Main Authors: Shinji Onda, Tomoyoshi Okamoto, Masaru Kanehira, Shuichi Fujioka, Tohru Harada, Hiroshi Hano, Masaharu Fukunaga, Katsuhiko Yanaga
Format: Article
Language:English
Published: Karger Publishers 2012-01-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://www.karger.com/Article/FullText/336199
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author Shinji Onda
Tomoyoshi Okamoto
Masaru Kanehira
Shuichi Fujioka
Tohru Harada
Hiroshi Hano
Masaharu Fukunaga
Katsuhiko Yanaga
author_facet Shinji Onda
Tomoyoshi Okamoto
Masaru Kanehira
Shuichi Fujioka
Tohru Harada
Hiroshi Hano
Masaharu Fukunaga
Katsuhiko Yanaga
author_sort Shinji Onda
collection DOAJ
description Autoimmune pancreatitis (AIP) can be difficult to distinguish from pancreatic cancer. We report a case of histopathologically proven AIP mimicking neuroendocrine tumor (NET) or pancreatic cancer in a 53-year-old man. He was referred to our hospital for further evaluation of a pancreatic mass detected on ultrasonography at a medical check-up. Abdominal ultrasonography showed a 15-mm hypoechoic mass located in the pancreatic body. Computed tomography revealed a tumor without any contrast enhancement, and magnetic resonance imaging demonstrated the mass to be hyperintense on diffusion-weighted image. Endoscopic retrograde cholangiopancreatography revealed slight dilatation of a branch of the pancreatic duct without stricture of the main pancreatic duct. The common bile duct seemed intact. Under suspicion of a non-functioning NET or malignant neoplasm, laparotomy was performed. At laparotomy, an elastic firm and well-circumscribed mass was found suggestive of a non-functioning NET, thus enucleation was performed. Histopathologically, the lesion corresponded to AIP.
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spelling doaj.art-3b641b234a6f4d4a85652a1582a1c39c2022-12-22T00:53:56ZengKarger PublishersCase Reports in Gastroenterology1662-06312012-01-0161404610.1159/000336199336199Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic CancerShinji OndaTomoyoshi OkamotoMasaru KanehiraShuichi FujiokaTohru HaradaHiroshi HanoMasaharu FukunagaKatsuhiko YanagaAutoimmune pancreatitis (AIP) can be difficult to distinguish from pancreatic cancer. We report a case of histopathologically proven AIP mimicking neuroendocrine tumor (NET) or pancreatic cancer in a 53-year-old man. He was referred to our hospital for further evaluation of a pancreatic mass detected on ultrasonography at a medical check-up. Abdominal ultrasonography showed a 15-mm hypoechoic mass located in the pancreatic body. Computed tomography revealed a tumor without any contrast enhancement, and magnetic resonance imaging demonstrated the mass to be hyperintense on diffusion-weighted image. Endoscopic retrograde cholangiopancreatography revealed slight dilatation of a branch of the pancreatic duct without stricture of the main pancreatic duct. The common bile duct seemed intact. Under suspicion of a non-functioning NET or malignant neoplasm, laparotomy was performed. At laparotomy, an elastic firm and well-circumscribed mass was found suggestive of a non-functioning NET, thus enucleation was performed. Histopathologically, the lesion corresponded to AIP.http://www.karger.com/Article/FullText/336199Fine-needle biopsyIgG4Differential diagnosisEndoscopic ultrasonography
spellingShingle Shinji Onda
Tomoyoshi Okamoto
Masaru Kanehira
Shuichi Fujioka
Tohru Harada
Hiroshi Hano
Masaharu Fukunaga
Katsuhiko Yanaga
Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer
Case Reports in Gastroenterology
Fine-needle biopsy
IgG4
Differential diagnosis
Endoscopic ultrasonography
title Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer
title_full Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer
title_fullStr Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer
title_full_unstemmed Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer
title_short Histopathologically Proven Autoimmune Pancreatitis Mimicking Neuroendocrine Tumor or Pancreatic Cancer
title_sort histopathologically proven autoimmune pancreatitis mimicking neuroendocrine tumor or pancreatic cancer
topic Fine-needle biopsy
IgG4
Differential diagnosis
Endoscopic ultrasonography
url http://www.karger.com/Article/FullText/336199
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