A Dual-Plasmid-Based CRISPR/Cas9-Mediated Strategy Enables Targeted Editing of pH Regulatory Gene <i>pacC</i> in a Clinical Isolate of <i>Trichophyton rubrum</i>

<i>Trichophyton rubrum</i> is the most prevalent causative agent responsible for 80–90% of all known superficial fungal infections in humans, worldwide. Limited available methods for genetic manipulations have been one of the major bottlenecks in understanding relevant molecular mechanis...

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Bibliographic Details
Main Authors: Sanchita Sanchaya Dey, Sivaprakash Ramalingam, Bhupesh Taneja
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/8/12/1241