Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial
Coronavirus disease 2019 (COVID-19) has led to an increasing number of patients in intensive care units (ICUs). The size of this post-ICU cohort will be unprecedented, with many patients vulnerable to post-intensive care syndrome. We analysed the respiratory and functional effects of a multidiscipli...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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European Respiratory Society
2023-01-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/9/1/00350-2022.full |
| _version_ | 1797809423359410176 |
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| author | Ana Cristina Carvalho Jorge Moreira Pedro Cubelo Pedro Cantista Catarina Aguiar Branco Bruno Guimarães |
| author_facet | Ana Cristina Carvalho Jorge Moreira Pedro Cubelo Pedro Cantista Catarina Aguiar Branco Bruno Guimarães |
| author_sort | Ana Cristina Carvalho |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) has led to an increasing number of patients in intensive care units (ICUs). The size of this post-ICU cohort will be unprecedented, with many patients vulnerable to post-intensive care syndrome. We analysed the respiratory and functional effects of a multidisciplinary rehabilitation programme on functional performance, in patients hospitalised in the ICU due to COVID-19. We conducted a randomised controlled clinical trial. 96 patients who fulfilled the eligibility criteria were randomised into control or intervention group. The control group received standard of care in the ICU, and the intervention group received a functional and respiratory rehabilitation protocol that included medical, nursing, physiotherapy and occupational therapy interventions. At discharge, the intervention group showed significantly better muscular strength and respiratory capacity, and significantly fewer days of hospitalisation (12.90±5.8 versus 15.60±6.7 days, p=0.037). At the 4- and 12-week follow-up, we applied our main outcome measure, the 6-min walk test (6MWT). The intervention group had significantly better results than the control group on the 6MWT at the 4-week follow-up (604±67 versus 571±57 m, p=0.018) and at the 12-week follow-up (639±53 versus 611±67 m, p=0.025). These results support the role of a multidisciplinary rehabilitation programme in COVID-19 patients hospitalised in the ICU and adds evidence that the implementation of rehabilitation programmes in ICUs could result in beneficial outcomes for critically ill patients. |
| first_indexed | 2024-03-13T06:52:30Z |
| format | Article |
| id | doaj.art-3b6c3e5cef7d4da69f9d5004106c1e89 |
| institution | Directory Open Access Journal |
| issn | 2312-0541 |
| language | English |
| last_indexed | 2024-03-13T06:52:30Z |
| publishDate | 2023-01-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | ERJ Open Research |
| spelling | doaj.art-3b6c3e5cef7d4da69f9d5004106c1e892023-06-07T13:30:43ZengEuropean Respiratory SocietyERJ Open Research2312-05412023-01-019110.1183/23120541.00350-202200350-2022Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trialAna Cristina Carvalho0Jorge Moreira1Pedro Cubelo2Pedro Cantista3Catarina Aguiar Branco4Bruno Guimarães5 Public Health Unit – Porto Oriental, ACeS Grande Porto VI, Porto, Portugal Department of Physical and Rehabilitation Medicine, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal Department of Physical and Rehabilitation Medicine, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Porto, Portugal Department of Physical and Rehabilitation Medicine, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal Department of Physical and Rehabilitation Medicine, Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Portugal Coronavirus disease 2019 (COVID-19) has led to an increasing number of patients in intensive care units (ICUs). The size of this post-ICU cohort will be unprecedented, with many patients vulnerable to post-intensive care syndrome. We analysed the respiratory and functional effects of a multidisciplinary rehabilitation programme on functional performance, in patients hospitalised in the ICU due to COVID-19. We conducted a randomised controlled clinical trial. 96 patients who fulfilled the eligibility criteria were randomised into control or intervention group. The control group received standard of care in the ICU, and the intervention group received a functional and respiratory rehabilitation protocol that included medical, nursing, physiotherapy and occupational therapy interventions. At discharge, the intervention group showed significantly better muscular strength and respiratory capacity, and significantly fewer days of hospitalisation (12.90±5.8 versus 15.60±6.7 days, p=0.037). At the 4- and 12-week follow-up, we applied our main outcome measure, the 6-min walk test (6MWT). The intervention group had significantly better results than the control group on the 6MWT at the 4-week follow-up (604±67 versus 571±57 m, p=0.018) and at the 12-week follow-up (639±53 versus 611±67 m, p=0.025). These results support the role of a multidisciplinary rehabilitation programme in COVID-19 patients hospitalised in the ICU and adds evidence that the implementation of rehabilitation programmes in ICUs could result in beneficial outcomes for critically ill patients.http://openres.ersjournals.com/content/9/1/00350-2022.full |
| spellingShingle | Ana Cristina Carvalho Jorge Moreira Pedro Cubelo Pedro Cantista Catarina Aguiar Branco Bruno Guimarães Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial ERJ Open Research |
| title | Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial |
| title_full | Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial |
| title_fullStr | Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial |
| title_full_unstemmed | Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial |
| title_short | Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial |
| title_sort | multidisciplinary rehabilitation in intensive care for covid 19 randomised controlled trial |
| url | http://openres.ersjournals.com/content/9/1/00350-2022.full |
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