Somatic mutation landscape in a cohort of meningiomas that have undergone grade progression

Somatic mutation landscape in a cohort of meningiomas that have undergone grade progression

Abstract Background A subset of meningiomas progress in histopathological grade but drivers of progression are poorly understood. We aimed to identify somatic mutations and copy number alterations (CNAs) associated with grade progression in a unique matched tumour dataset. Methods Utilising a prospe...

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Bibliographic Details
Main Authors: Sarah A Cain, Bernard Pope, Stefano Mangiola, Theo Mantamadiotis, Katharine J Drummond
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cancer
Subjects:
Meningioma
Next generation sequencing
Anaplastic
Atypical
Malignant
Online Access:https://doi.org/10.1186/s12885-023-10624-9

Internet

https://doi.org/10.1186/s12885-023-10624-9

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