Effects of Selenium-Enriched Probiotics on Heart Lesions by Influencing the mRNA Expressions of Selenoproteins and Heat Shock Proteins in Heat Stressed Broiler Chickens
Selenium is one of the most vital trace elements regulating various body functions. Herein, we observe the effects of selenium-enriched probiotics on heart lesion in broiler chickens under high ambient temperature and explore the underlying mechanisms. Four different groups of broiler chickens were...
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| Format: | Article |
| Language: | English |
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University of Agriculture, Faisalabad
2016-11-01
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| Series: | Pakistan Veterinary Journal |
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| Online Access: | http://pvj.com.pk/pdf-files/36_4/460-464.pdf |
| Summary: | Selenium is one of the most vital trace elements regulating various body functions. Herein, we observe the effects of selenium-enriched probiotics on heart lesion in broiler chickens under high ambient temperature and explore the underlying mechanisms. Four different groups of broiler chickens were fed a corn-soybean basal diet having no Se supplementation (Con group), basal diet with the addition of probiotics (P group), a basal diet with Se supplementation in the form of sodium selenite (SS group, 0.30mg Se/kg) and basal diet with the addition of selenium enriched probiotics (SP group, 0.30mg Se/kg). The results showed that P, SS, or SP supplementation significantly (P<0.05) up-regulated mRNA expression of selenoproteins (GPx1, GPx4) and down-regulated heat shock proteins (Hsp60, Hsp70 and Hsp90) in heart as compared to Con, P and SS diets. Herein, we suggest that SP product can serve as a feasible nutritive supplement, capable of protecting the heart from toxic effect of oxidative stress in summer season. |
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| ISSN: | 0253-8318 2074-7764 |